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Green growth in the post-Copenhagen climate

Global climate change stands out from most environmental problems because it will span generations and force us to think in new ways about intergenerational fairness. It involves the delicate problem of complex coordination between countries on a truly global scale. As long as fossil fuels are too cheap, climate change policy will engage all major economies. The costs are high enough to make effic

Challenging disparities in capacity development for disaster risk reduction

Although capacity development has been identified as the means to substantially reduce global disaster losses, it is a challenge for external partners to facilitate the development of sustainable capacities for disaster risk reduction in disaster-prone countries. The purpose of this study is to investigate potential gaps between how leading professionals approach such capacity development and guid

SEFAS The Self-Reported Foot and Ankle Score

Background: Patient-reported outcome (PRO) instruments are used in all medical disciplines to evaluate patients with different diseases and also to follow results after treatments such as surgery. Currently there is no generally accepted and fully validated PRO instrument for the foot and ankle. Aims: To translate the New Zealand Ankle Questionnaire into a Swedish version, [the Self-Reported Foot

Functional analyses of complement convertases using c3 and c5-depleted sera.

C3 and C5 convertases are central stages of the complement cascade since they converge the different initiation pathways, augment complement activation by an amplification loop and lead to a common terminal pathway resulting in the formation of the membrane attack complex. Several complement inhibitors attenuate convertase formation and/or accelerate dissociation of convertase complexes. Functiona

System Simulations to Evaluate the Potential Efficiency of Humid Air Motors

In the quest for efficiency improvement in heavy duty truck engines, waste heat recovery could play a valuable role. The evaporative cycle is a waste heat recovery technology aimed at improving efficiency and decreasing emissions. A humid air motor (HAM) uses the waste heat from the exhaust of the engine to humidify the inlet air; this humid air, with higher specific heat, reduces NOx emission to

Pion Emission in H-2,C-12,Al-27(gamma,pi+) Reactions at Threshold

The very first data from MAX-lab in Lund, Sweden on pion photoproduction at threshold energies are presented. The decrease of the total π+ yield in γ+12C, 27Al reactions below 200 MeV as well as the dσ/dΩ cross-section data essentially follow the predictions of an intranuclear-cascade model with an attractive potential for the pion–nucleus interaction. However, View the MathML source, cross-sectio

Modelling Allelic and DNA Copy Number Variations using Continuous-index Hidden Markov Models

Popular Abstract in Swedish DNA i form av kromosomer finns i cellerna och innehåller information som styr flertalet av kroppens funktioner. Människor har vanligtvis 23 par kromosomer, där den ena kromosomen i ett par härstammar från personens mamma och den andra från dess pappa. DNA ser ut som en vriden stege där stegpinnarna består av nukleotidbaspar. I cancerceller kan det finnas bitar av kromIn human cells there are usually two copies of each chromosome, but in cancer cells abnormalities could exist. The differences consist of segments of chromosomes with an altered number of copies. There can be deletions as well as amplifications and the lengths of the segments can also vary. Localising the deviant regions is of great importance for increasing the knowledge of the disease. In this t

Determination of the isomeric fraction in a postaccelerated radioactive ion beam using the coupled decay-chain equations

A method based on the coupled decay-chain equations for extracting the isotopic and the isomeric composition of a postaccelerated radioactive ion beam is presented and demonstrated on a data set from a Coulomb excitation experiment. This is the first attempt of analyzing the content of a postaccelerated radioactive ion beam using this technique. The beam composition is required for an absolute nor

Effects of galectins and antibodies in HIV infection; Novel Assays

The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. An important tool in detecting and studying bnAbs, are neutralization assays. Here we d

Main factors controlling microbial community structure and function after reclamation of a tailing pond with aided phytostabilization

Reclamation on bare tailing ponds has the potential to represent soil genesis in Technosols favoring the understanding of the changes of microbial communities and function. In this study we used phytostabilization aided with calcium carbonate and pig slurry/manure to reclaim an acidic bare tailing pond with the aim of investigating the effect of amending and different species on microbial communit

Mechanisms of microbial-host interaction during asymptomatic bacteriuria

Popular Abstract in Swedish Mer än hälften av alla kvinnor har haft en urinvägsinfektion. Infektionen uppkommer när bakterier når urinblåsan och börjar växa. Immunförsvaret känner igen bakterierna, reagerar med en inflammation och symptom som sveda, trängningar och smärtor i nedre magtrakten uppstår. Om bakterierna klättrar upp till njurarna sprider sig inflammationen dit och orsakar ryggsmärtor oUrinary tract infections (UTIs) present an interesting and relevant model for studying microbial adaptation. After establishing significant numbers, the bacteria either cause severe disease, or an asymptomatic carrier state resembling the normal flora at other mucosal sites. Patients with asymptomatic bacteriuria (ABU) are protected from re-infection if the strain that they carry outcompetes more

Protonation of the proximal histidine ligand in heme peroxidases.

The heme peroxidases have a histidine group as the axial ligand of iron. This ligand forms a hydrogen bond to an aspartate carboxylate group by the other nitrogen atom in the side chain. The aspartate is not present in the globins and it has been suggested that it gives an imidazolate character to the histidine ligand. Quantum chemical calculations have indicated that the properties of the heme si

All wurtzite (In,Ga)As-(Ga,Mn)As core-shell nanowires

Structural and magnetic properties of (In,Ga)As-(Ga,Mn)As core−shell nanowires grown by molecular beam epitaxy on GaAs(111)B substrate with gold catalyst have been investigated. (In,Ga)As core nanowires were grown at high temperature (500 °C) whereas (Ga,Mn)As shells were deposited on the {11̅00} side facets of the cores at much lower temperature (220 °C). High-resolution transmission electron mic

The uPA receptor in ovarian cancer. Regulation by EGF and the estrogen responsive membrane receptor GPR30. Soluble uPAR in diagnosis and prognosis.

Cell migration is the first step of the invasive process, which is part of the malignant phenotype, and the uPA receptor (uPAR) plays a central role in cell migration. We studied the role of EGF and estrogen on cell migration and uPAR expression in ovarian cancer cell lines. We also analyzed the diagnostic and prognostic value of cleaved forms of the uPAR in plasma from patients with ovarian tumor