The aggregation of peptides into amyloid fibrils is associated with several diseases, including Alzheimer's and Parkinson's disease. Because hydrophobic interactions often play an important role in amyloid formation, the presence of various hydrophobic or amphiphilic molecules, such as lipids, may influence the aggregation process. We have studied the effect of a fatty acid, linoleic acid, on the

Previous studies have shown significant differences in the enhancement of the star formation rate (SFR) and star formation efficiency (SFE = SFR/Mmol) between spiral–spiral and spiral–elliptical mergers. In order to shed light on the physical mechanism of these differences, we present NOEMA observations of the molecular gas distribution and kinematics (linear resolutions of ∼2 kpc) in two represen

Purpose: This cross-sectional study of 2450 children with cerebral palsy aimed to analyse the prevalence and association of scoliosis, windswept hips, hip and knee contractures. Methods: Logistic regression was used to estimate associations with pain, postural asymmetries, and ability to change position for children at Gross Motor Function Classification System (GMFCS) levels I–V, aged 0–18 years.

Context: The European Association of Urology (EAU) has released an updated version of the guidelines on non–muscle-invasive bladder cancer (NMIBC). Objective: To present the 2021 EAU guidelines on NMIBC. Evidence acquisition: A broad and comprehensive scoping exercise covering all areas of the NMIBC guidelines since the 2020 version was performed. Databases covered by the search included Medline,

Background: Radical prostatectomy reduces mortality among patients with localised prostate cancer. Evidence on whether different surgical techniques can affect mortality rates is lacking. Objective: To evaluate functional and oncological outcomes 8 yr after robot-assisted laparoscopic prostatectomy (RALP) and open retropubic radical prostatectomy (RRP). Design, setting, and participants: We enroll

Context. The physical processes driving the formation of Galactic spiral arms are still under debate. Studies using open clusters favour the description of the Milky Way spiral arms as long-lived structures following the classical density wave theory. Current studies comparing the Gaia DR2 field stars kinematic information of the solar neighbourhood to simulations, find a better agreement with sho

This dissertation is about visual perception of material properties and their role in preparation for object handling. Usually before an object is touched or picked-up we estimate its size and shape based on visual features to plan the grip size of our hand. After we have touched the object, the grip size is adjusted according to the provided haptic feedback and the object is handled safely. Simil

Carbon capture using amine-based absorption is an established technology for the separation of gaseous CO2. It is used in the upgrading of gaseous fuels, and it has also been suggested that it could play a crucial role in the mitigation of climate change through post-combustion carbon capture and sequestration (CCS), and by creating carbon sinks through bioenergy CCS. One drawback of the existing

We consider the solution of the subset sum problem based on a parallel computer consisting of self-propelled biological agents moving in a nanostructured network that encodes the computing task in its geometry. We develop an approximate analytical method to analyze the effects of small errors in the nonideal junctions composing the computing network by using a Gaussian confidence interval approxim

FinEstBeAMS (Finnish-Estonian Beamline for Atmospheric and Materials Sciences) is a multidisciplinary beamline constructed at the 1.5 GeV storage ring of the MAX IV synchrotron facility in Lund, Sweden. The beamline covers an extremely wide photon energy range, 4.5-1300 eV, by utilizing a single elliptically polarizing undulator as a radiation source and a single grazing-incidence plane grating mo

Previous studies have shown that addition of potassium chloride (KCl) reduces soot concentration and primary particle size. To improve the understanding of this phenomenon, this work focuses on investigating the influence of KCl addition on formation of polycyclic aromatic hydrocarbons (PAHs), assumed to be precursors of soot. The method used is laser-induced fluorescence (LIF), for which differen

Flexible colonoscopy remains the prime mean of screening for colorectal cancer (CRC) and the gold standard of all population-based screening pathways around the world. Almost 60% of CRC deaths could be prevented with screening. However, colonoscopy attendance rates are affected by discomfort, fear of pain and embarrassment or loss of control during the procedure. Moreover, the emergence and global

Nanowire solar cells have the potential to reach the same efficiencies as the world-record III-V solar cells while using a fraction of the material. For solar energy harvesting, large-area nanowire solar cells have to be processed. In this work, we demonstrate the synthesis of epitaxial InP nanowire arrays on a 2 inch wafer. We define five array areas with different nanowire diameters on the same

OBJECTIVES: Preterm birth has been linked with increased risk of autism spectrum disorder (ASD); however, potential causality, sex-specific differences, and association with early term birth are unclear. We examined whether preterm and early term birth are associated with ASD in a large population-based cohort. METHODS: A national cohort study was conducted of all 4 061 795 singleton infants born

Lead-free halide perovskites have triggered interest in the field of optoelectronics and photocatalysis because of their low toxicity, and tunable optical and charge-carrier properties. From an application point of view, it is desirable to develop stable multifunctional lead-free halide perovskites. We have developed a series of Cs2PtxSn1−xCl6 perovskites (0≤x≤1) with high stability, which show sw

Predation risk is often invoked to explain variation in stress responses. Yet, the answers to several key questions remain elusive, including the following: (1) how predation risk influences the evolution of stress phenotypes, (2) the relative importance of environmental versus genetic factors in stress reactivity and (3) sexual dimorphism in stress physiology. To address these questions, we explo

In this work we compute for the first time the so-called Complete-NLO predictions for top-quark pair hadroproduction in association with at least one isolated photon (tt¯ γ). We also compute NLO QCD+EW predictions for the similar case with at least two isolated photons (tt¯ γγ) and for single-top hadroproduction in association with at least one isolated photon. In addition, we complement our resul

Introduction: The risk for cardiovascular diseases and other comorbidities increases with the number of unhealthy lifestyle factors in the general population. However, information on the combined number of unhealthy lifestyle factors in people with rheumatoid arthritis (RA) is scarce. Objectives: To study lifestyle factors and the association between disease impact and two or more unhealthy lifest

Background: The COVID-19 pandemic called for rapidly considerable changes in the healthcare system. Healthcare professionals from different departments within the hospital settings were enrolled in the emergency preparedness. This study, therefore, aimed to explore the healthcare professionals’ experiences attending the ICU-preparedness and caring for patients with COVID-19 during the initial stag