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Higher Serum Free T4 Is Associated With Increased Risk of Mortality and Cerebrovascular Events in Elderly Men

Background: It is unclear whether thyroid hormone levels are associated with the risk of mortality, cardiovascular disease (CVD) events, or cancer in men with normal TSH. Objectives: We analyzed if serum free T4 (FT4) or TSH is associated with the risk of mortality, incident CVD events, or cancer in Swedish men. Methods: Elderly men (n = 1801; mean age 75 years) in the Gothenburg and Malmö subcoho

Acute effects of 150 mg caffeine on subjective, physiological, and behavioral components of anxiety in panic disorder and healthy controls – A randomized placebo-controlled crossover trial

Background: Caffeine in doses above 400 mg, approximately four cups of coffee, induces panic attacks in 50% of individuals with panic disorder (PD) and elevates anxiety, but it is not known how individuals with PD respond to normally consumed doses or how caffeine interacts with emotional tasks. Aims: We hypothesized that 150 mg caffeine would increase subjective anxiety (primary outcome) as well

Occupational risk of COVID-19 related hospital admission in Skåne, Sweden : A register-based cohort study

PURPOSE: Given the paucity of data regarding workplace risk of COVID-19, particularly from countries with limited lockdowns, we aimed to quantify the occupational risks of COVID-19-related hospital admission among workers in Sweden.METHODS: We identified 607,179 employed individuals, 20-69 years of age, in Skåne, Sweden. From December 31st, 2019-December 31st 2021, 2,633 incident COVID-19-related

Analytical model for rapid simulation of ultrasound optical tomography images based on mean photon path lengths

Ultrasound optical tomography enables noninvasive characterization of tissue and lesions up to 5 cm below the skin surface, by enhancing diffuse optical tomography with ultrasound focusing resolution and an increased number of measurement points. For optimal clinical imaging, it is essential to be able to reconstruct tissue optical properties in real time during in vivo measurements, and therefore

Online, spatiotemporally resolved characterization of aluminum atom puffing during the ignition of micron-sized aluminum wire

This paper presents the first online, in-situ experimental evidence of the puffing behavior of aluminium (Al) atoms during the ignition of a micron-sized Al wire. As the protective alumina (Al2O3) layer ruptures, spatially resolved laser absorption measurements reveal the outward puffing of Al atoms from the molten Al wire core. These Al atoms then react with the surrounding oxidizers, leading to

Multi-coincidence set-up for nuclear forensics with Si-strip and Compton-suppressed HPGe detectors

A radiation detection system combining a single-sided silicon strip detector (SSSD) and a high-purity germanium (HPGe) COMPEX detector module together with its anti-Compton shield (ACS) was set up at Lund University for environmental sample measurements. This system enables high sensitivity ––-coincidence analysis, enhancing the identification level of radionuclides in environmental samples. A com

Validity of Self-Rating Questionnaires Used for Assessing Self-Disorders? A Systematic Review

Introduction: Self-disorders designate a group of nonpsychotic, trait-like, anomalous self-experiences. The “gold standard” for assessing self-disorders is largely considered to be the Examination of Anomalous Self-Experience (EASE). The EASE must be conducted as a semistructured interview, and it requires substantial knowledge of psychopathology and excellent interviewing skills. To bypass these

Extracellular vesicle impact on immunity following blood transfusion

Purpose of the Review: Recent insights into extracellular vesicles (EVs) derived from platelet (PC) and red blood cell concentrates (RBC), which form during blood product processing and storage. Recent Findings: EVs impact transfusion outcomes by modulating immune and inflammatory responses. Acting as lipid mediators and expressing adhesion molecules, EVs contribute to immune signaling via cytokin

Dispersions of weakly charged thermoresponsive microgels at high densities

Poly-N-isopropylacrylamide-based microgels in aqueous dispersion exhibit a pronounced thermoresponse that allows to control their size and thus the volume fraction via temperature. Here, we study the phase behavior of aqueous dispersions of weakly charged microgels with small silica cores, employing different scattering techniques. From temperature- and concentration-dependent experiments in prese

Constraints on the hadronic light-by-light tensor in corner kinematics for the muon g − 2

The dispersive approach to the hadronic light-by-light contribution to the muon g − 2 involves an integral over three virtual photon momenta appearing in the light-by-light tensor. Building upon previous works, we systematically derive short-distance constraints in the region where two momenta are large compared to the third, the so-called Melnikov-Vainshtein or corner region. We include gluonic c

Fatigue in adults with congenital heart disease aged over 40 years

Background: Fatigue is a symptom that has been described among adult patients with congenital heart disease (CHD), but the prevalence and impact of fatigue on the patient's daily life has been poorly studied. This study (i) examines the prevalence of fatigue in patients aged over 40 years with moderately complex or complex congenital heart disease compared to controls and (ii) explores the relatio

Improved TDS forecasting in data-scarce regions using CEEMDAN and AI-driven hydro-climatic analysis

Total dissolved solids (TDS) are a key water quality parameter, reflecting the concentration of dissolved salts in aquatic systems. Accurate TDS forecasting is essential for sustainable water resource management, particularly in data-scarce regions. This study proposes a novel and generalized AI-based framework to forecast TDS up to six months ahead using a limited set of hydro-climatic input vari

The anomalous magnetic moment of the muon in the Standard Model : an update

We present the current Standard Model (SM) prediction for the muon anomalous magnetic moment, aμ, updating the first White Paper (WP20) [1]. The pure QED and electroweak contributions have been further consolidated, while hadronic contributions continue to be responsible for the bulk of the uncertainty of the SM prediction. Significant progress has been achieved in the hadronic light-by-light scat

Force, Fear, and Consent to Marriage : Supplications to the Apostolic Penitentiary in the late Middle Ages

In this paper I investigate the petitions to invalidate forced marriages submitted to the Apostolic Penitentiary during the pontificate of Pope Innocent VIII (1484-1492). The supplications will be analyzed both in relation to the late medieval scholarly discussion of force and fear as impediment to marriage, and in relation to the lived reality that emerges in the petitioner’s narratives. The Peni

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Abstract in French:À travers une approche philologique, cet article tire de l’oubli un duc français qui s’est réfugié en Suède après la Révolution française et qui contribue de manière inattendue et méconnue à l’histoire transnationale entre la France et la Suède. Proche d’Axel de Fersen et introduit dans le cercle amical de la reine Charlotte, le duc de Pienne était en Suède lors du meurtre de FeThrough the use of philology, this article recovers the figure of a French duke who took refuge in Sweden after the French Revolution and who contributes in an unexpected and little-known way to the transnational history between France and Sweden. Close to Axel von Fersen and introduced into Queen Charlotte’s circle of friends, the duc de Pienne was in Sweden at the time of Fersen’s murder, and su

Immunosuppressants for IgG4-related disease

OBJECTIVES: This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of immunosuppressants with or without corticosteroids compared to corticosteroid monotherapy for the treatment of IgG4-related disease in people 18 years or older.

Longer scans boost prediction and cut costs in brain-wide association studies

A pervasive dilemma in brain-wide association studies1 (BWAS) is whether to prioritize functional magnetic resonance imaging (fMRI) scan time or sample size. We derive a theoretical model showing that individual-level phenotypic prediction accuracy increases with sample size and total scan duration (sample size × scan time per participant). The model explains empirical prediction accuracies well a

Studies in Earth-system economic history

The urgency of global climate change and other geological-scale anthropogenic impacts also suggests new perspectives on economic history. This thesis argues for the inclusion into economic history of more Earth-system centred feedbacks, both in terms of environmental and climatic consequences and environmental and climatic causes, where consequences in one realm may again become causal in the othe

Comprehensive multifaceted analysis for unveiling the driving factors of groundwater decline

Groundwater, as a vital water resource in arid and semi-arid regions, plays a crucial role in sustaining human livelihoods, agriculture, and industry. Over recent decades, these areas have witnessed rapid groundwater depletion, raising concerns about resource sustainability. This research provides a comprehensive analysis of the factors contributing to the decline in groundwater levels (GWL) withi