We have studied the production of neutral high-Rydberg (HR) fragments from the CH4 molecule at the C 1s -> 3p excitation and at the C 1s ionization threshold. Neutral fragments in HR states were ionized using a pulsed electric field and the resulting ions were mass-analyzed using an ion time-of-flight spectrometer. The atomic fragments C(HR) and H(HR) dominated the spectra, but molecular fragments

Objective: Cancer quality registers are attracting increasing attention as important, but still underutilized sources of clinical data. To optimize the use of registers in quality assurance and improvement, data have to be rapidly collected, collated and presented as actionable, at-a-glance information to the reporting departments. This article presents a dashboard performance report on select qua

Abstract in UndeterminedInformation fusion via multimodal inverse problems and different sensors is addressed using a Fisher information analysis approach. The Fisher information measure is inherently additive, and it facilitates an appropriate weighting of the measurement data that is statistically optimal and can hence be useful with reconstruction algorithms in geophysical sensing. Given that t

The importance of having correct structural descriptions is becoming ever clearer, not only in drug discovery research, but also in the development of new advanced materials. Here the key to optimizing properties lies in understanding the structure-property relationships. Without a correct description theoretical calculations will inevitably fail to describe and explain any experimental observatio

The debate on non‐human future‐oriented cognition has long revolved around the question whether such cognition at all occurs. Closer inspection reveals just how much cognition in general—down to its simplest forms—is geared toward predicting the future in a bid to maintain homeostasis and fend off entropy. Over the course of life's existence on Earth, evolution and natural selection have, through

BACKGROUND: Studies concerning the relationship between distal radius fracture malunion and a persistent arm-related disability have produced conflicting results. QUESTIONS/PURPOSES: We investigated (1) how arm-related disability changes during the first 2 years after a fracture and (2) whether fracture malunion causes persistent disability. METHODS: One hundred twenty-three patients with distal r

The maldigestion and malabsorption of fat in infants fed milk formula results due to the minimal production of pancreatic lipase. Thus, to investigate lipid digestion and absorption and mimic the situation in newborns, a young porcine exocrine pancreatic insufficient (EPI) model was adapted and validated in the present study. A total of thirteen EPI pigs, aged 8 weeks old, were randomised into thr

Central government bailouts of local governments are commonly viewed as a recipe for local fiscal indiscipline, as local governments learn that the center will come to the rescue in times of trouble. However, little is known about the consequences of bailouts granted conditional on local governments first making efforts to improve the situation. We examine a case in which the Swedish central gover

Purpose: We investigated whether inhibition of interleukin 6 (IL-6) has therapeutic activity in ovarian cancer via abrogation of a tumor-promoting cytokine network. Experimental Design: We combined preclinical and in silico experiments with a phase 2 clinical trial of the anti-IL-6 antibody siltuximab in patients with platinum-resistant ovarian cancer. Results: Automated immunohistochemistry on ti

INTRODUCTION.: Cyclic adenosine 3'5' monophosphate (cAMP) is produced by adenylate cyclase after activation by, e.g., vasoactive intestinal polypeptide or prostaglandin E1 (PGE1). The cAMP-degrading phosphodiesterase 4 (PDE4) is expressed in the vagina and clitoris, but no information is available on the functional role for PDE4-related signals in the female neurovascular genital response. AIM.: T

We consider a model for the Higgs sector with two scalar doublets and a softly broken Z(2) symmetry, the Stealth Doublet Model. This model can be seen as a generalization of the Inert Doublet Model. One of the doublets is the Higgs doublet that participates in electroweak symmetry breaking and couples to fermions. The other doublet does not couple to fermions at tree level and does not acquire a v

This study analyzes (a) the relation between injury severities, the age of the bicyclist and the speed environment at accident locations (mean travel speed of the traffic flow involved in the accident) where a bicyclist was struck by a motorized vehicle and (b) how these relations differ from those for struck pedestrians. Accident data from Sweden for the years 2004-2008 was used to identify accid

This paper analyzes the properties of panel unit root tests based on recursively detrended data. The analysis is conducted while allowing for a (potentially) non-linear trend function, which represents a more general consideration than the current state of affairs with (at most) a linear trend. A new test statistic is proposed whose asymptotic behavior under the unit root null hypothesis, and the

Dietary chloroplast thylakoids have previously been found to reduce food intake and body weight in animal models, and to change metabolic profiles in humans in mixed-food meal studies. The aim of this study was to investigate the modulatory effects of thylakoids on glucose metabolism and appetite-regulating hormones during an oral glucose tolerance test in pigs fed a high fat diet.

Although recent studies suggest that high intakes of meat and heme iron are risk factors for several types of cancer, studies in relation to esophageal adenocarcinoma (EAC) are scarce. Previous results in the European Prospective Investigation into Cancer and Nutrition (EPIC) based on a relatively small number of cases suggested a positive association between processed meat and EAC. In this study,

Reference attribute grammars (RAGs) provide a practical declarative means to implement programming language compilers and other tools. RAGs have previously been extended to support nonterminal attributes (also known as higher-order attributes), circular attributes, and context-dependent declarative rewrites of the abstract syntax tree. In this previous work, interdependencies between these extensi

Objective: To examine whether the ratio of the second and fourth metacarpal bone length (MC2:MC4) in subjects with prior meniscectomy of the knee is associated with radiographic hand and knee osteoarthritis (OA) and its progression. Design: We assessed 219 subjects (175 men and 44 women) twice with a follow-up time ranging from 4 to 10 years. Participants had all undergone prior meniscectomy. The