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Investigating late-stage particle production in pp collisions with balance functions

Balance functions have been regarded in the past as a method of investigating the late-stage hadronization found in the presence of a strongly-coupled medium. They are also used to constrain mechanisms of particle production in large and small collision systems. Charge balance functions for inclusive and identified particle pairs are reported as a function of charged particle multiplicity in proto

Where to restore – an approach to spatial prioritization of connectivity forests for forest landscape restoration

With two centuries of forestry, natural forests in boreal Swedenare rare and strongly fragmented. Hence, restoration aiming toimprove conditions for forest biodiversity is needed. However,to ensure landscape connectivity – where to restore is a criticalconcern.Our study objective was to identify connectivity forest thatthrough restoration support connectivity and biodiversity. Thestudy area coversWith two centuries of forestry, natural forests in boreal Sweden are rare and strongly fragmented. Hence, restoration aiming to improve conditions for forest biodiversity is needed. However, to ensure landscape connectivity – where to restore is a critical concern.Our study objective was to identify connectivity forest that through restoration support connectivity and biodiversity. The study area

Suppressing Halide Segregation Via Dual-Anchoring Strategy for 31.20% Perovskite/Silicon Tandem Solar Cells

The efficiency and stability of wide bandgap (WBG) perovskite solar cells (PSCs) are constrained by photo-induced halide segregation and severe non-radiative recombination, which significantly impedes the advancement of high-efficiency and stable perovskite/silicon tandem solar cells (PSTSCs). In this work, a potassium 4-sulfonic-1,8-naphthalic anhydride salt (4S-NAPS), featuring dual-anchoring si

Antineutrophil cytoplasmic antibody-associated vasculitis : insights into relapse risk and future management directions

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) has a relapsing-remitting course and, even with the availability of effective maintenance therapies such as rituximab, relapse rates remain high. Relapse is associated with the accrual of organ damage stemming from both the underlying disease and from the effects of AAV treatments; thus, early detection and proactive prevention

Mild or moderate hemophilia is not always a mild or moderate bleeding disorder : Back to the clinical phenotype

In a previous paper, a comprehensive clinicopathologic approach to mild and moderate bleeding disorders (MBD) was proposed by an international working group (IWG) as a part of a project promoted by the European Hematology Association (EHA) on the development of guidelines on the various MBDs. A single pre-diagnosis grade 4 bleeding event according to the ISTH-BAT scale or a comparable event after

Riddaren med svärdet : Ett unikt gravfynd på Lilla torg i Halmstad

Vid de arkeologiska utgrävningarna av franciskankonventet på Lilla torg i Halmstad påträffades många gravar, däribland en man som hade fått ett stort svärd med sig i graven. Han låg begravd bredvid en kvinna och en yngling . I artikeln undersöks vem denne man kan ha varit, hans släktband och sociala omständigheter samt varför han begravts just på denna plats. De tre gravlagda kopplas till den dans

STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies

The interdisciplinary nature of microbiome research, coupled with the generation of complex multi-omics data, makes knowledge sharing challenging. The Strengthening the Organization and Reporting of Microbiome Studies (STORMS) guidelines provide a checklist for the reporting of study information, experimental design and analytical methods within a scientific manuscript on human microbiome research

Cell-weighted polygenic risk scores are associated with β-amyloid and tau biomarkers in Alzheimer's disease

The molecular pathways influencing the build-up of β-amyloid and tau pathology in Alzheimer's disease are unclear. To investigate how the involvement of different cell types influences β-amyloid and tau, we utilized single-cell RNA-seq data to derive cell-weighted polygenic risk scores. We included participants from the BioFINDER-1 study, including cognitively unimpaired (N = 734) individuals and

The emergence of labour utopias : Solidarity, visibility and agency in the Swedish Municipal Workers’ Union strike

In 2003, the Swedish Municipal Workers’ Union (Kommunal) called a nationwide strike, demanding a pay rise for all members in the public sector. Drawing on oral history interviews with workplace representatives and local union officials, the article examines how the struggle enabled changes in subjectivity, generating utopian visions for increased visibility and agency for municipal workers. This p

Digital Public Diplomacy and the Illusion of the Online/Offline Divide

The rise of social media platforms in the early 2010’s marked a shift in public diplomacy practice resulting in the emergence of “digital public diplomacy.” This chapter explores the evolution of digital public diplomacy by emphasizing digital culture as a significant source of social and political change in a broader societization of diplomacy. Moving beyond a narrow focus on digitalization, it a

Reduced protein solubility - cause or consequence in amyloid disease?

In this perspective, we ask the question whether the apparently lower solubility of specific proteins in amyloid disease is a cause or consequence of the protein deposition seen in such diseases. We focus on Alzheimer's disease and start by reviewing the experimental evidence of disease-associated reduction in the measured concentration of amyloid β peptide, Aβ42, in cerebrospinal fluid. We propos

Improving taxonomic inference from ancient environmental metagenomes by masking microbial-like regions in reference genomes

Ancient environmental DNA is increasingly vital for reconstructing past ecosystems, particularly when paleontological and archaeological tissue remains are absent. Detecting ancient plant and animal DNA in environmental samples relies on using extensive eukaryotic reference genome databases for profiling metagenomics data. However, many eukaryotic genomes contain regions with high sequence similar

Toward an integrated research agenda for cryospheric change : a socio-glaciology approach

Non-technical summary. As glaciers shrink and disappear, the benefits they provide to people may also be fading. This makes it more important than ever to look closely at how melting glaciers affect both the environment and the communities that depend on them. To truly understand what is being lost- or even gained- we need to study glaciers from many angles. This includes looking at the science of

Improved droplet elongation model and value for surface tension of AuSi

Surface tension is crucial for nanowire vapor liquid solid (VLS) growth models and simulations of growth under external stimuli. A promising method involving imaging droplet deformation under an external electric field has previously been used to report the surface tension of the AuSi eutectic catalyst on Si-nanowires. However, simplified assumptions in this approach led to a significantly lower v

Challenges in Elucidating HIV-1 Genetic Diversity in the Middle East and North Africa : A Review Based on a Systematic Search

The extensive genetic diversity of HIV-1 represents a major challenge to public health interventions, treatment, and successful vaccine design. This challenge is particularly pronounced in the Middle East and North Africa (MENA) region, where limited data among other barriers preclude the accurate characterization of HIV-1 genetic diversity. The objective of this review was to analyze studies cond

The equivocal opposite effects of lower and higher body mass index at diagnosis on radiographic joint damage progression in early rheumatoid arthritis : an inception cohort study over 15 years

Objective To investigate the effect of Body Mass Index (BMI) on long-term radiographic damage in an inception rheumatoid arthritis (RA) cohort. Methods The study population, n=1813, originated from the observational Better AntiRheumatic FarmacoTherapy cohort. X-rays of hands and feet at inclusion, 1, 2, 5, 8 and 15 years were quantified for erosion score (ES), joint space narrowing (JSN) and the s

Lower dislocation rate in total hip arthroplasty for femoral neck fracture after transition from a conventional cup to a dual mobility cup

Introduction: Dislocation is a major complication of total hip arthroplasty (THA) for femoral neck fractures (FNFs). Dual mobility cups (DMCs) are in clinical practice for patients at risk of dislocation in primary-and revision arthroplasty. This study investigated whether changing routines from conventional THA (cTHA) to DMC for fracture patients at our orthopaedic unit resulted in a reduced disl

Chromatin interaction-based annotation of regulatory elements reveals dynamic promoter-enhancer interactions in lymphocyte development

Stage- and lineage-specific gene expression patterns are controlled by a complex interplay between transcription factors, the epigenetic landscape, and the three-dimensional (3D) structure of the DNA. The 3D structure allows for the formation of DNA loops that juxtaposition distal regulatory elements to the promoters, allowing for tight control of gene expression. Developing a tool to facilitate t

Hydrogenation of CO2 to Methanol by a Nickel Pincer Catalyst and Mechanistic Investigations by Density Functional Theory Studies

The hydrogenation of CO2 into methanol by a nickel pincer catalyst has been studied in both aqueous and solid–gas phases. Hydrogenation occurs at the moderate temperatures of 60–95 °C. The solid–gas phase reaction is found to be more efficient than the aqueous reaction. At 95 °C and 1 MPa of H2/CO2 (3:1), 18 μmol of methanol is generated in the optimized solid–gas phase reaction versus 10 μmol in

Seasonal analysis and environmental risk assessment of selected emerging pollutants in the Vaal River catchment area of South Africa

The presence of pharmaceuticals, especially antibiotics, in aquatic environments can significantly contribute to the rise of antibiotic resistance, presenting a critical global public health challenge. This study investigates the presence of four selected antibiotics and an antiretroviral drug (nevirapine) in the Vaal River in South Africa. Grab samples collected at nine sampling sites across four