Significance This project describes the existence of previously unknown non-GPI-anchored CD59 isoforms required for insulin secretion, named CD59-IRIS-1 and CD59-IRIS-2, and finds reduced expression of CD59-IRIS isoforms in human diabetic islets, showing a link between dysregulation of IRIS isoforms and defects in insulin secretion in diabetic patients. These data open a path for future studies in

In this presentation I will discuss the potential of narrative methods to remedy the epistemic injustice that drug users experience within the drug-averse Swedish context, departing from my work with drug-involved women in Sweden. Drug users and, more generally, drug-active individuals have been traditionally considered as unreliable sources of information, requiring the researcher to spend consid

Zinc is an element of importance in many research fields within astronomy and astrophysics, from cosmology to stellar atmosphere dynamics. With the aim of improving three decades old measurements of zinc lines of astrophysical interest, emission spectra of Zn I and Zn II have been recorded using a Fourier Transform Spectrometer with a hollow cathode light source. Revised energies for previously kn

This letter proposes a co-designed millimeter-wave (mm-wave) and sub-6GHz antenna system. The antenna system consists of four 28GHz mm-wave arrays with reconfigurable radiation patterns and two sub-6GHz antennas fed with two corner capacitive coupling elements (CCEs). Each corner CCE is formed by the connected ground planes of two mm-wave arrays in the shared-aperture configuration. The two CCEs a

Sufficiency has long been marginalized in the public and political sustainability discourse. Since attempts to reduce CO2 emissions in the long term have so far fallen short of expectations, sufficiency has recently approached the forefront of scientific and social debates about a »good life«. In addition to a strict reduction target, the sufficiency strategy promises psychological well-being and

With stringent effluent requirements and the implementation of new processes for micropollutant removal, it is increasingly important for wastewater treatment plants (WWTPs) to understand the factors affecting effluent quality. Phages (viruses infecting prokaryotes) are abundant in the biological treatment processes. They can contribute to organic carbon in the treated effluent both because they a

BACKGROUND: Although the impact of pancreatic infections in acute pancreatitis has been studied extensively, there are no population-based data on extrapancreatic infections and their potential relation to organ failure. We aimed to study the occurrence of pancreatic and extrapancreatic bacterial infections in acute pancreatitis and their relation to patient outcome. PATIENTS AND METHODS: All pati

Ants use memorized visual scenes to navigate towards food sources and to return to their nest. Two new studies show that both of these behaviors fail when structures of the ant brain known as mushroom bodies are chemically disrupted, confirming long-held assumptions about the location of ants’ visual navigation memories.

It is generally found that human capital has had positive effects on industrial development and economic growth, but the relationship between formal education, work practice, industrial development and economic growth, and the relationships between them over time, remains unclear, largely because of a lack of empirical evidence. This note argues that an investigation of the Danish dairy industry c

Background:The Mediterranean diet (MD) has been proposed as a means for cancer prevention, but little evidence has been accrued regarding its potential to prevent pancreatic cancer. We investigated the association between the adherence to the MD and pancreatic cancer risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.Methods:Over half a million participants

Objective To systematically identify and validate published colorectal cancer risk prediction models that do not require invasive testing in two large population-based prospective cohorts. Design Models were identified through an update of a published systematic review and validated in the European Prospective Investigation into Cancer and Nutrition (EPIC) and the UK Biobank. The performance of th

En redogörelse av en enkel undersökning som visar att en övervägande majoritet av de tillfrågade föredrar en mer klassisk version av byggnad i centrala Helsingborg framför den modernistiska som förverkligas.

En reflektion kring ett politiskt beslut som togs i Göteborg 2020. Politikerna kom överens om att nu måste det nya som byggs vid Skeppsbron i Göteborg få en klassisk utformning. De menar att med klassisk och traditionell arkitektur blir invånarna och besökare nöjdare. Beslutet retade upp många arkitekter.

En reflektion kring värdet av en attraktiv stadskärna i tider