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Effect of lactobacilli on paracellular permeability in the gut.

Paracellular permeability is determined by the complex structures of junctions that are located between the epithelial cells. Already in 1996, it was shown that the human probiotic strain Lactobacillus plantarum 299v and the rat-originating strain Lactobacillus reuteri R2LC could reduce this permeability in a methotrexate-induced colitis model in the rat. Subsequently, many animal models and cell

Genetics of Type 2 Diabetes and Metabolic Syndrome: From Genome Wide Linkage Scan and Candidate Genes to Genome Wide Association Studies

Type 2 diabetes (T2D) and metabolic syndrome (MetS) are major health problems associated with cardiovascular disease. Both diseases are influenced by a combination of genetic and environmental factors. The aim of this thesis was to identify genetic risk factors for T2D, particularly T2D associated with obesity, and for MetS. To achieve this goal, we 1) followed-up a region linked to obese T2D in a

Strangeness production at low Q(2) in deep-inelastic ep scattering at HERA

The production of neutral strange hadrons is investigated using deep-inelastic scattering events measured with the H1 detector at HERA. The measurements are made in the phase space defined by the negative four-momentum transfer squared of the photon 2 < Q(2) < 100 GeV2 and the inelasticity 0.1 < y < 0.6. The K-s(0) s and Lambda((Lambda) over bar) production cross sections and their ratios are dete

Severe Streptococcus pyogenes disease in Europe; epidemiology and clinical manifestations

Streptococcus pyogenes, gives rise from mild skin infections and pharyngitis, to life threatening infections like bacteraemia, cellulitis, puerperal sepsis, meningitis, pneumonia, necrotizing fasciitis (NF), and streptococcal toxic-like shock syndrome (STSS), or nonsuppurative sequelae, rheumatic fever and glomerulonephritis. In 2002, the first multinational network for invasive GAS disease survei

Creating creative environments

There is empirical evidence indicating that trust in research is decreasing. If distrust is justified, this is a good thing; if not, it is a cause of concern. A basic question concerns the reasons for, ant the causes of, distrust. Which are they, what do they mean, and how reliable are they? The papers and presentations in this volume focus on external and internal factors contributing to distrus

Att förklara människan : Diskurser i populärvetenskapliga TV-program

The principle aim of the study is to describe, analyze and problemize the ways in which television science documentaries (within a public service context) discursively represent scientific theories, research results and conclusions about the origins of human nature and the causes of human behavior. The study covers 25 programs broadcasted by SVT and UR during a period of four years, 2002-2005, and

Rational design of HIV vaccines and microbicides: report of the EUROPRISE network annual conference 2010

Novel, exciting intervention strategies to prevent infection with HIV have been tested in the past year, and the field is rapidly evolving. EUROPRISE is a network of excellence sponsored by the European Commission and concerned with a wide range of activities including integrated developmental research on HIV vaccines and microbicides from discovery to early clinical trials. A central and timely t

Front- and backstage in social media

Oversharing of information about one's private life or the private lives of others appears to be an oft-noted phenomenon in the context of social media. This paper aims at answering the following question: What is it in social media as media and in the communicative situation of the person using them that facilitate oversharing of private information? A comparative analysis of face-to-face interac

The Anatomy and Physics of Z(DR) Columns: Investigating a Polarimetric Radar Signature with a Spectral Bin Microphysical Model

Polarimetric radar observations of deep convective storms frequently reveal columnar enhancements of differential reflectivity Z(DR). Such "Z(DR) columns" can extend upward more than 3 km above the environmental 0 C level, indicative of supercooled liquid drops being lofted by the updraft. Previous observational and modeling studies of Z(DR) columns are reviewed. To address remaining questions, th

On the sensitivity of rotational CARS N-2 thermometry to the Herman-Wallis factor

Purely rotational spectral signals of coherent anti-Stokes Raman scattering (CARS) from nitrogen molecules are studied as a function of the vibration-rotation interaction that weakens the rigid rotor approximation under which the dominant terms of the Raman cross section are calculated. The effect of the vibration-rotation interaction is quantified by means of the Herman-Wallis (HW) factor, and di

Internal and External Knowledge and Introduction of Export Varieties

Firms in local industries maintain their capability to generate new export varieties by simultaneously exploiting internal and external knowledge resources. The paper introduces the notion variety triplet' to distinguish individual export varieties, where a triplet is a unique combination of a firm, a product code and a destination country. For each date, the set of variety triplets in each local

Measurement of t(t)over-bar production with a veto on additional central jet activity in pp collisions at root s=7 TeV using the ATLAS detector

A measurement of the jet activity in t (t) over bar events produced in proton-proton collisions at a centre-of-mass energy of 7 TeV is presented, using 2.05 fb(-1) of integrated luminosity collected by the ATLAS detector at the Large Hadron Collider. The t (t) over bar events are selected in the dilepton decay channel with two identified b-jets from the top quark decays. Events are vetoed if they

Early life factors and being overweight at 4 years of age among children in Malmo, Sweden

Background: Rising rates of obesity and overweight is an increasing public health problem all over the world. Recent research has shown the importance of early life factors in the development of child overweight. However, to the best of our knowledge there are no studies investigating the potential synergistic effect of early life factors and presence of parental overweight on the development of c

Troponin I and Creatine Kinase MB do not provide comparable information after PCI

Objectives. To compare cardiac troponin I (cTnI) and creatine kinase-MB (CK-MB) after PCI in cases with normal baseline levels of both biomarkers. Design. cTnI and CK-MB after PCI were stratified as multiples of the 99 3x99%URL in 58/486 patients (12%) and cTnI > 3x99%URL in 292/487 patients (60%). cTnI was > 10x99%URL in all cases with infarction according to CK-MB but CK-MB was often normal desp

RF Spatial Modulation Using Antenna Arrays

A new method of spatial linear modulation is presented for the RF signal modulation. The constant envelope and phase modulated signals are transmitted to an antenna array and then combined in space; the linear modulation is realized at the same time. The concentric antenna pairs are applied to eliminate the mismatch of phase delay among the modulated signals from different antenna pairs. The measu

Octave illusion elicited by overlapping narrowband noises.

The octave or Deutsch illusion occurs when two tones, separated by about one octave, are presented simultaneously but alternating between ears, such that when the low tone is presented to the left ear the high tone is presented to the right ear and vice versa. Most subjects hear a single tone that alternates both between ears and in pitch; i.e., they hear a low pitched tone in one ear alternating

Sparse Estimation Of Spectroscopic Signals

This work considers the semi-parametric estimation of sparse spec- troscopic signals, aiming to form a detailed spectral representation of both the frequency content and the spectral line widths of the oc- curring signals. Extending on the recent FOCUSS-based SLIM al- gorithm, we propose an alternative prior for a Bayesian formulation of this sparse reconstruction method, exploiting a proposed sui