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Objectives: Our goal was to provide data on the economic burden and health-related quality of life (HRQOL) of patients with cystic fibrosis (CF) and their caregivers in Europe. Methods: A cross-sectional study was carried out on adults and children with CF in eight European countries. Patients completed an anonymous questionnaire regarding their socio-demographic characteristics, use of healthcare

We present some experimental results describing microstructural evolution in commercially pure titanium during severe plastic deformation by twist extrusion (TE). In particular, we show that increasing the number of TE passes leads to the decrease of the grain size d in both orthogonal and parallel cross-sections of the work piece. For example, if in its original state titanium has d ∼ 25 μm, then

One of the most effective methods for obtaining bulk ultrafine-grained materials is severe plastic deformation that is typically done using equal channel angular pressing. In this work we describe and analyze a new method for obtaining severe plastic deformations proposed by the first author. The method is based on direct extrusion and was called "twist extrusion" The main idea of the method is to

We present an experimental study of the kinematics of twist extrusion (TE) and show that TE has the following properties: (i) as in equal-channel angular pressing (ECAP), the mode of deformation in twist extrusion is simple shear. Unlike in ECAP, there are two shear planes; one of them is perpendicular and the other is parallel to the specimen axis. (ii) The following processes are present during

This study examines the long-run relationship between finance and economic growth in Sweden from the 1830s until the 1990s using recently developed econometric techniques for tests of cointegration. The role of investment, education and technological progress (patents) is accounted for as well in order to assess the relative importance of the development of the financial system for growth performaThis study examines the long-run relationship between finance and economic growth in Sweden from the 1830s to the 1990s using recently developed econometric techniques for tests of cointegration. The role of investment, education and technological progress (patents) is accounted for as well in order to assess the relative importance of the development of the financial system for growth performance

The present work deals with achieving improvement in the mechanical properties of SUS304L stainless steel through the application of a unique microstructure design termed as 'Harmonic structure', and establishing a co-relationship between various microstructural characteristics and mechanical properties. Harmonic structure essentially means a bimodal grain size distribution with a specific periodi

Aluminium-titanium (Al/Ti) composite sheets were fabricated via asymmetric accumulative roll bonding (AARB), which capitalises on additional shear to enhance plastic deformation. Multi-layers of Al alloy (AA1050) and commercially-pure Ti sheets were alternatively stacked and rolled-bonded with varied roll diameter ratios (dr) ranging from 1 to 2, for up to four passes. Annealing of selected compos

High-cyclic fatigue life in ultra-fine grained materials fabricated by equal channel angular pressing (ECAP) suffers from a specific shear texture induced during the fabrication as has been demonstrated in the present study on the example of pure copper. This texture promotes orientation of the easy glide crystallographic planes to be aligned parallel to the shear plane in ECAP. If specimens for t

Most of severe plastic deformation processes involve strain reversal. Till now quite big number of researches has been done on indirect study of its role, which discusses the effect of loading path in ultra-fine grained structure formation. This work is aimed to study directly the role of the strain reversal in grain refinement by severe plastic deformation. A 99.99% purity aluminum was processed

Twist extrusion (TE) is known as one of newly developed, but still moderately studied severe plastic deformation methods. This research was initiated to conduct a detailed study of structure-properties relationship evolution during TE processing. The evolution of macrostructure, Vickers hardness and tensile properties was studied in 99.99% purity aluminum during twist extrusion processing at room

Purpose of the Study: To identify policy gaps in the delivery and availability of assistive health technology (AHT) and medical devices (MD) for aging populations, particularly in low- and middle-income countries (LMICs). Design and Methods: The findings presented in this paper are the results of several narrative overviews. They provide a contextual analysis of the conclusions and evidence from W