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BACKGROUND: Recent advances now allow detection of brain-specific proteins in blood, including neurofilament light chain (NfL), a marker of axonal pathology, and glial fibrillary acidic protein (GFAP), indicative of astrocytic activation. Given the evidence of astroglial pathology and neuronal dysfunction in bipolar disorder, and ongoing debates on neuroprogression, we investigated plasma NfL and
Defaulter tracing policies for Prevention of Mother-to-Child Transmission (PMTCT) services are vital for achieving the global goal of zero new HIV infections. However, little is known about their implementation. This qualitative study explores the role of tracers—community volunteers, retention workers, and mentor mothers—in implementing such policy across six facilities in Western Kenya. It usesDefaulter tracing policies for Prevention of Mother-to-Child Transmission (PMTCT) services are vital for achieving the global goal of zero new HIV infections. However, little is known about their implementation. This qualitative study explores the role of tracers—community volunteers, retention workers, and mentor mothers—in implementing such policy across six facilities in Western Kenya. It uses
Renin from plasma, kidney, and recombinant sources was previously demonstrated to cleave C3 to C3a and C3b. C3a was generated at a similar rate to that by C3 convertase, and C3 cleavage was inhibited by the renin inhibitor aliskiren. Renin endogenously produced by Calu6 cells also led to C3 deposition on cells. These results have been challenged by another group suggesting that recombinant renin d
Magneto-responsive soft films constitute a fascinating class of smart materials and devices capable of performing various tasks, such as micromanipulation or transport, noninvasive surgery, and sensing. These components are fabricated by incorporating magnetic materials into flexible substrates. In this context, arranging magnetic particles into elongated chains exhibiting shape anisotropy has sho
Nanochains (NCs) made up of a one-dimensional arrangement of magnetic anoparticles (NPs) exhibit anisotropic properties with potential for various applications. Herein, using a novel self-assembly method we directly integrate single NCs onto desired substrates including devices. We present a nanoscopic analysis of magnetization reversal in 1D linear NP arrays by combining x-ray microscopy, magnet
The widespread use of artificial intelligence technologies in border management throughout the European Union has significant human rights implications that extend beyond the commonly examined issues of privacy, non-discrimination and data protection. This article explores these overlooked impacts through three critical frameworks: the erosion of freedom of thought, the disempowerment of individua
Artificial intelligence (AI) is increasing being deployed across various sectors in society. While bringing progress and promise to scientific discovery, public administration, healthcare, transportation and human well-being generally, artificial intelligence can also exacerbate existing forms of human vulnerabilities and can introduce new vulnerabilities through the interplay of AI inferences, pr
Accurate mapping of vegetation canopy height and biomass distribution is essential for effective forest monitoring, climate change mitigation, and sustainable forestry. Here we present high-resolution remote sensing-based canopy height (10 m resolution) and above ground biomass (AGB, 50 m resolution) maps for the forests of the Iberian Peninsula from 2017 to 2021, using a deep learning framework t
Rapport från en serie rundabordssmtal under Chatham House Rules. Samtlen handlade om Sveriges utmaningar med och förutsättningar för att tillvarata AI-utvecklingen.
Redovisningen av svenska resultat i den internationella undersökningen Global Entrepreneurship Monitor (GEM).
Fires in buildings present life-threatening scenarios where rapid decision-making and timely evacuation are paramount. Significant advancements in understanding evacuation decision-making have been made, though little research addresses the role of memory in this process. Memory plays a crucial role in how individuals perceive, interpret, and respond to information which, during fire evacuation, c
ObjectiveWe aimed to investigate whether health-promoting text messages sent to patients with hypertension in primary care could affect lifestyle habits, and if the Theory of Planned Behavior could be used to identify moderators of intervention effects.MethodsFrom September 2020 to December 2022, patients with hypertension were randomly selected from the patient register at 10 Swedish primary heal
