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Remembering desirable futures? : Civil defence memories and everyday life in Sweden and the United Kingdom

This chapter explores how the concept of sociotechnical imaginaries can be used to examine civil defence as remembered. In focus stand oral histories testifying to the entanglement of civil defence in everyday life. The chapter employs a historical ethnography approach, using interviews and questionnaires collected between 2006 and 2012 in Sweden and the UK. The analysis, which departs from the th

Gear tolerancing for simultaneous optimization of transmission error and contact pressure

With electrification of vehicles comes an increasing demand on low noise, which for gears translates to transmission error. In this paper, static transmission error, STE, is found for a large number of manufacturing error combinations belonging to different tolerance classes, with focus on those typically used in the automotive industry. There is a lack of studies found in the scientific literatur

Fetal Echocardiographic Dimension Indices: Important Predictors of Postnatal Coarctation

The aim of the study is to identify reliable quantitative fetal echocardiographic predictors for postnatal development of coarctation (CoA). In this retrospective study, we included 65 fetuses with a prenatally suspected, isolated CoA, born 2010–2018. Dimensions of the cardiac structures, aortic, and ductal arches expressed as ratios and Z-scores were analyzed in relation to outcome. Fetuses that

Natural clusters of tuberous sclerosis complex (TSC)-associated neuropsychiatric disorders (TAND) : new findings from the TOSCA TAND research project

BACKGROUND: Tuberous sclerosis complex (TSC)-associated neuropsychiatric disorders (TAND) have unique, individual patterns that pose significant challenges for diagnosis, psycho-education, and intervention planning. A recent study suggested that it may be feasible to use TAND Checklist data and data-driven methods to generate natural TAND clusters. However, the study had a small sample size and da

The global scale, distribution and growth of aviation : Implications for climate change

Prior to the COVID-19 crisis, global air transport demand was expected to triple between 2020 and 2050. The pandemic, which reduced global air travel significantly, provides an opportunity to discuss the scale, distribution and growth of aviation until 2018, also with a view to consider the climate change implications of a return to volume growth. Industry statistics, data provided by supranationa

Understanding N2O emissions in african ecosystems : Assessments from a semi-arid savanna grassland in senegal and sub-tropical agricultural fields in Kenya

This study is based on the analysis of field-measured nitrous oxide (N2 O) emissions from a Sahelian semi-arid grassland site in Senegal (Dahra), tropical humid agricultural plots in Kenya (Mbita region) and simulations using a 1D model designed for semi arid ecosystems in Dahra. This study aims at improving present knowledge and inventories of N2 O emissions from the African continent. N2 O emiss

The Transition From Stochastic to Deterministic Bacterial Community Assembly During Permafrost Thaw Succession

The Northern high latitudes are warming twice as fast as the global average, and permafrost has become vulnerable to thaw. Changes to the environment during thaw leads to shifts in microbial communities and their associated functions, such as greenhouse gas emissions. Understanding the ecological processes that structure the identity and abundance (i.e., assembly) of pre- and post-thaw communitiesThe Northern high latitudes are warming twice as fast as the global average, and permafrost has become vulnerable to thaw. Changes to the environment during thaw leads to shifts in microbial communities and their associated functions, such as greenhouse gas emissions. Understanding the ecological processes that structure the identity and abundance (i.e., assembly) of pre- and post-thaw communities

Extracellular Vesicles Released by Enterovirus-Infected EndoC-βH1 Cells Mediate Non-Lytic Viral Spread

While human enteroviruses are generally regarded as a lytic virus, and persistent non-cytolytic enterovirus infection in pancreatic beta cells has been suspected of playing a role in type 1 diabetes pathogenesis. However, it is still unclear how enteroviruses could exit the pancreatic beta cell in a non-lytic manner. This study aimed to investigate the role of beta cell-derived extracellular vesic

Immunosuppressive treatment after solid organ transplantation and risk of post-transplant cutaneous squamous cell carcinoma

BACKGROUND: The risk of cutaneous squamous cell carcinoma (CSCC) is found to be substantially increased after organ transplantation. The association with specific immunosuppressive regimens has been previously investigated, but results are not concordant. We aimed to clarify the relationship between separate immunosuppressive drugs, drug load, timing and risk of post-transplant CSCC.METHODS: A pop

No association between infections, HLA type and other transplant-related factors and risk of cutaneous squamous cell carcinoma in solid organ transplant recipients

Recipients of solid organ transplants are at a markedly increased risk of cutaneous squamous cell carcinoma (SCC). We investigated potential associations between post-transplant infections, HLA type, and other transplant-related factors and risk of SCC, taking immuno-suppressive treatment into account. A population-based case-control study was conducted. All patients who developed SCC during follo

Direct Conversion of Human Stem Cell-Derived Glial Progenitor Cells into GABAergic Interneurons

Glial progenitor cells are widely distributed in brain parenchyma and represent a suitable target for future therapeutic interventions that generate new neurons via in situ reprogramming. Previous studies have shown successful reprogramming of mouse glia into neurons whereas the conversion of human glial cells remains challenging due to the limited accessibility of human brain tissue. Here, we hav

Tobacco use, body mass index, and the risk of leukemia and multiple myeloma : a nationwide cohort study in Sweden

In a prospective cohort study of more than 330,000 Swedish construction workers, we explored the effect of tobacco smoking, oral moist snuff use, and body mass index (BMI) on the risk of developing leukemia (excluding chronic lymphocytic leukemia) and multiple myeloma (MM). Study subjects were participants of a health surveillance system within the building industry. Record linkage to the nationwi

Tobacco use, body mass index and the risk of malignant lymphomas--a nationwide cohort study in Sweden

In the search for risk factors involved in the etiology of lymphoproliferative malignancies there is still inconsistent evidence regarding effects of smoking tobacco, and the role of smokeless tobacco is poorly investigated. New evidence indicates that excess body weight increases the risk of NHL and HD. To determine if tobacco use of various forms and high Body Mass Index (BMI) affect the occurre

Time trends in risk and risk determinants of non-Hodgkin lymphoma in solid organ transplant recipients

Organ transplantation increases risk of non-Hodgkin lymphoma (NHL), but long-term risk and time trends have seldom been evaluated. Immunosuppressive drug load is an important risk determinant, but the details are unclear. We studied NHL risk in a nationwide Swedish cohort of 11 081 graft recipients transplanted 1970-2008. Relative risks (RRs) were estimated within the cohort and versus the general

Polymer electrolyte fuel cell system level modelling and simulation of transient behavior

In this paper, a system level model for a polymer electrolyte fuel cell (PEFC) system, which is capable of characterizing transient behavior using the control volume method, is developed. Three different cases based on different mass transfer assumptions in the cathode channel are explicitly discussed, i.e., considering the presence of 1) only oxygen, 2) both oxygen and nitrogen or 3) oxygen as we

The risk for cutaneous malignant melanoma, melanoma in situ and intraocular malignant melanoma in relation to tobacco use and body mass index

BACKGROUND: The incidence of cutaneous malignant melanoma (CMM) and melanoma in situ (MIS) has been increasing during the last 50 years. Malignant melanoma (MM) is also the most common intraocular malignancy (IMM). Besides ultraviolet radiation, the cause of these tumours is largely unknown.OBJECTIVES: We designed a study to examine the effect of body mass index (BMI) and tobacco use on the risk f

Tobacco smoking, snuff dipping and the risk of cutaneous squamous cell carcinoma : a nationwide cohort study in Sweden

We investigated whether tobacco use causes cutaneous squamous cell carcinoma (CSCC) in a large cohort study with complete and long-term follow-up. A total of 756 incident cases occurred in a cohort of 337,311 men during a 30-year follow-up period, but no association was found between any kind of smoking tobacco use and CSCC risk, nor any risk change with increasing dose, duration or time since smo