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Cohort Profile: The Maule Cohort (MAUCO)

Published 4 September 2020 The Maule Cohort (MAUCO) is the first prospective population-based cohort of cardiovascular disease (CVD) and cancer in central Chile. The rationale for this cohort is based on the social, environmental and health characteristics of an under-studied rural population at high risk for chronic diseases. Read more at https://academic.oup.com/ije/article/49/3/760/5807634

https://www.lupop.lu.se/article/cohort-profile-maule-cohort-mauco - 2025-01-29

Cohort Profile: The Kaloleni/Rabai Community Health and Demographic Surveillance System

Published 4 September 2020 In many resource-constrained settings, availability of reliable vital statistics and health information is limited by lack of proper system for civil registration and health information. This is further limited by the fact that the majority of population health events, such as births, morbidity and mortality, occur outside the reach of these systems. In particular, obtai

https://www.lupop.lu.se/article/cohort-profile-kalolenirabai-community-health-and-demographic-surveillance-system - 2025-01-29

Cohort Profile: The Finnish Gestational Diabetes (FinnGeDi) Study

Published 5 September 2020 The Finnish Gestational Diabetes (FinnGeDi) study is a multicentre study that considered Finnish women who gave birth in 2009–12, as well as their children and the children’s fathers. The study period was after the introduction of new Finnish national comprehensive screening guidelines for gestational diabetes mellitus (GDM). The study consisted of two arms: a prospectiv

https://www.lupop.lu.se/article/cohort-profile-finnish-gestational-diabetes-finngedi-study - 2025-01-29

Daily School Physical Activity Improves Academic Performance

Published 5 September 2020 Physical activity (PA) may improve brain development, cognition, concentration and academic performance. In this prospective controlled intervention study, we increased the level of PA in 338 children aged 6–8 years at study start, from the Swedish standard of 60 min per week to 200 min per week (40 min daily). The intervention continued in all nine compulsory school yea

https://www.lupop.lu.se/article/daily-school-physical-activity-improves-academic-performance - 2025-01-29

Poor psychological health and 5-year suicide mortality: A population-based prospective cohort study.

Published 6 September 2020 The objective was to investigate associations between the General Health Questionnaire with twelve sub-items (GHQ-12) and prospective five-year suicide mortality. The two commonly used GHQ-12 cut-offs (2/3 and 3/4) were analyzed. METHOD:The 2008 public health survey, which was conducted in the autumn of 2008 in Scania, southern Sweden, is based on a postal questionnaire

https://www.lupop.lu.se/article/poor-psychological-health-and-5-year-suicide-mortality-population-based-prospective-cohort-study - 2025-01-29

Per- and Polyfluoroalkyl Substances in Early Pregnancy and Risk for Preeclampsia: A Case-Control Study in Southern Sweden

Published 6 September 2020 Preeclampsia is one of the most common causes of perinatal and maternal morbidity/mortality. One suggested environmental risk factor is exposure to endocrine-disrupting pollutants such as per- and polyfluoroalkyl substances (PFAS). The present case-control study in southern Sweden aims to investigate the hypothesized association between serum concentrations of PFAS in ea

https://www.lupop.lu.se/article/and-polyfluoroalkyl-substances-early-pregnancy-and-risk-preeclampsia-case-control-study-southern - 2025-01-29

Invasive infections with Fusobacterium necrophorum including Lemierre's syndrome: an 8-year Swedish nationwide retrospective study

Published 7 September 2020 We aimed to evaluate the nationwide incidence and a potential increase in invasive infections with Fusobacterium necrophorum. Secondly, we aimed to describe epidemiology, clinical characteristics and outcomes for the different presentations: Lemierre's syndrome (LS), invasive head and neck-infection without LS and invasive non-head and neck-infection. Read more at https:

https://www.lupop.lu.se/article/invasive-infections-fusobacterium-necrophorum-including-lemierres-syndrome-8-year-swedish-nationwide - 2025-01-29

Calculating the Starting Age for Screening in Relatives of Patients With Colorectal Cancer Based on Data From Large Nationwide Data Sets

Published 7 September 2020 Although colorectal cancer (CRC) screening guidelines acknowledge the need for earlier screening for high-risk individuals, such as those with family history of CRC, there is limited information on how many years earlier these high-risk individuals should be screened; current practice is based on weak evidence. We aimed to provide risk-adapted recommendations on the star

https://www.lupop.lu.se/article/calculating-starting-age-screening-relatives-patients-colorectal-cancer-based-data-large-nationwide - 2025-01-29

Fetal Programming of Semen Quality (FEPOS) Cohort – A DNBC Male-Offspring Cohort

Published 8 September 2020 Prenatal exposures may contribute to male infertility in adult life, but large-scale epidemiological evidence is still lacking. The Fetal Programming of Semen quality (FEPOS) cohort was founded to provide means to examine if fetal exposures can interfere with fetal reproductive development and ultimately lead to reduced semen quality and reproductive hormone imbalances i

https://www.lupop.lu.se/article/fetal-programming-semen-quality-fepos-cohort-dnbc-male-offspring-cohort - 2025-01-29

Multiple sclerosis among first‐ and second‐generation immigrant groups in Sweden

Published 8 September 2020 We included adults aged 18 years and older in Sweden in first‐generation (n = 6 042 891) and second‐generation (n = 4 860 469) sub‐studies. MS was defined via two diagnoses in the Swedish National Patient Register. MS risk was estimated by Cox regression, with hazard ratios (HRs) and 95% confidence intervals (CI), in different immigrant groups, using Swedish‐born as refe

https://www.lupop.lu.se/article/multiple-sclerosis-among-first-and-second-generation-immigrant-groups-sweden - 2025-01-29

Geographical and sociodemographic differences in discontinuation of medication for Chronic Obstructive Pulmonary Disease – A Cross-Classified Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)

Published 9 September 2020 While discontinuation of COPD maintenance medication is a known problem, the proportion of patients with discontinuation and its geographical and sociodemographic distribution are so far unknown in Sweden. Therefore, we analyse this question by applying an innovative approach called multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA). Rea

https://www.lupop.lu.se/article/geographical-and-sociodemographic-differences-discontinuation-medication-chronic-obstructive - 2025-01-29

Global systematic review of primary immunodeficiency registries

Published 9 September 2020 During the last 4 decades, registration of patients with primary immunodeficiencies (PID) has played an essential role in different aspects of these diseases worldwide including epidemiological indexes, policymaking, quality controls of care/life, facilitation of genetic studies and clinical trials as well as improving our understanding about the natural history of the d

https://www.lupop.lu.se/article/global-systematic-review-primary-immunodeficiency-registries - 2025-01-29

Research Services presents: Meet the Funders

Published 2 September 2020 Research Services is pleased to announce a pair of webinars on research funding from some of the biggest funders in Sweden. These webinars will give you a chance to hear straight from the funders about their schemes and funding philosophy, and they will also answer your questions directly. The webinars are open to all researchers at Lund, and no prior knowledge of the fu

https://www.lupop.lu.se/article/research-services-presents-meet-funders - 2025-01-29

Population Registry of Esophageal and Stomach Tumours in Ontario (PRESTO): protocol for a multicentre clinical and pathological database including 25 000 patients

Published 10 September 2020 Oesophagogastric cancers carry a high mortality, economic burden and rising incidence. There is a need to monitor and improve care for this disease. Pathologic information is a cornerstone of cancer diagnosis, treatment and prognosis. Few population-based studies combine pathology information and clinical outcomes. The objective of this study is to develop a clinical an

https://www.lupop.lu.se/article/population-registry-esophageal-and-stomach-tumours-ontario-presto-protocol-multicentre-clinical-and - 2025-01-29

The Importance of Reference Centers and Registries for Rare Diseases: The Example of Alpha-1 Antitrypsin Deficiency

Published 11 September 2020 Alpha-1 antitrypsin deficiency (AATD) is a rare and underdiagnosed disease that is associated with the development of liver disease in adults and children and pulmonary emphysema in adults. Several studies have shown that there is limited knowledge about the disease and its diagnosis among health care providers, and there is an important inequity in the access to specia

https://www.lupop.lu.se/article/importance-reference-centers-and-registries-rare-diseases-example-alpha-1-antitrypsin-deficiency - 2025-01-29

Effects of pay-for-performance on prescription of hypertension drugs among public and private primary care providers in Sweden

Published 11 September 2020 This study exploits policy reforms in Swedish primary care to examine the effect of pay-for-performance (P4P) on compliance with hypertension drug guidelines among public and private health care providers. Using provider-level outcome data for 2005–2013 from the Swedish Prescription Register, providers in regions using P4P were compared to providers in other regions in

https://www.lupop.lu.se/article/effects-pay-performance-prescription-hypertension-drugs-among-public-and-private-primary-care - 2025-01-29

Effect of medical treatment in patients with systemic right ventricle

Published 12 September 2020 Congenitally corrected and surgical atrial redirected transposition of the great arteries (TGA) represents states where the morphological right ventricle serves as a systemic ventricle (S-RV). The S-RV is prone to failure, but data on medical treatment on this problem is limited. The purpose of this study was to evaluate the survival in adults with S-RV, with or without

https://www.lupop.lu.se/article/effect-medical-treatment-patients-systemic-right-ventricle - 2025-01-29

Personal History of Diabetes as Important as Family History of Colorectal Cancer for Risk of Colorectal Cancer: A Nationwide Cohort Study

Published 12 September 2020 Diabetes mellitus (DM) and colorectal cancer (CRC) share some risk factors, including lifestyle and metabolic disturbances. We aimed to provide in-depth information on the association of CRC risk, especially early-onset CRC, with DM, family history of CRC, and age at DM diagnosis. Read more at https://journals.lww.com/ajg/Fulltext/2020/07000/Personal_History_of_Diabetes

https://www.lupop.lu.se/article/personal-history-diabetes-important-family-history-colorectal-cancer-risk-colorectal-cancer - 2025-01-29