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Mast Cell Proteases Promote Diverse Effects on the Plasminogen Activation System and Wound Healing in A549 Alveolar Epithelial Cells

Tissue damage, epithelial alterations, and intraepithelial presence of mast cells (MCs) are characteristics of asthma pathogenesis. Increased alveolar infiltration of MC populations has also been identified as a feature of asthma and other chronic respiratory diseases. The asthma associated receptor, urokinase plasminogen activator receptor (uPAR), has been shown to regulate bronchial epithelial r

Microgrids through the Energy-Water-Food Security Nexus in La Guajira, Colombia : Increasing water and food security or jeopardizing groundwater levels?

This study analyses the impacts of small-scale renewable energy technologies on Colombian rural indigenous communities in La Guajira through an Energy-Water-Food Security (EWF) Nexus lens. Due to the high-water scarcity in the region, special attention lays on identifying the water-related trade-offs when increasing access to energy technologies. Recognizing the importance of the indigenous people

Comparable Long-Term Tumor Control for Hypofractionated FLASH Versus Conventional Radiation Therapy in an Immunocompetent Rat Glioma Model

Purpose: To ensure a clinical translation of FLASH radiation therapy (FLASH-RT) for a specific tumor type, studies on tumor control and toxicity within the same biological system are needed. In this study, our objective was to evaluate tumor control and toxicity for hypofractionated FLASH-RT and conventional radiation therapy (CONV-RT) in an immunocompetent rat glioma model. Methods and Materials:

Haemophilia A and B - evaluation of the Swedish prophylactic regimen by magnetic resonance imaging

INTRODUCTION: Sweden has been a pioneer in the prophylactic treatment of haemophilia. Magnetic resonance imaging (MRI) can detect small changes in joints and can therefore give an indication of a risk of developing arthropathy.AIM: To use MRI to evaluate the outcome of the Swedish 'high-dose regimen' and correlate the findings to age, bleeds, joint score and physical activity.METHODS: The study gr

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In this (Danish) article, Tabita Rosendal provides an overview of China's use of Buddhist diplomacy in Sri Lanka, arguing that the CCP is utilizing Buddhist strategic narratives in order to pave the way for the Belt and Road Initiative's (BRI) smooth implementation. She summarizes the BRI's progress in Sri Lanka, China's use of Buddhist diplomacy, as well as China's Buddhist strategic narratives,

Assessing Healthcare Workers’ Knowledge and Their Confidence in the Diagnosis and Management of Human Monkeypox : A Cross-Sectional Study in a Middle Eastern Country

The ongoing multi-country human monkeypox (HMPX) outbreak was declared as a public health emergency of international concern. Considering the key role of healthcare workers (HCWs) in mitigating the HMPX outbreak, we aimed to assess their level of knowledge and their confidence in diagnosis and management of the disease, besides the assessment of their attitude towards emerging virus infections fro

The development and certification of a single fuel high speed marine CI engine on methanol

Reducing emissions is a priority for all vessels, as global warming is accelerating, and emissionregulations are becoming ever stricter. Still, waterborne transport is the most energy efficientalternative in many cases, and in some cases the only alternative. Vessels in the maritime sectoroperate far from electric charging infrastructure, and have large demands in terms of autonomy, so tobe able t

Differences in subjective well-being between individuals with distinct Joint Personality (temperament-character) networks in a Bulgarian sample

Background. Personality is the major predictor of people’s subjective well-being (i.e., positive affect, negative affect, and life satisfaction). Recent research in countries with high-income and strong self-transcendent values shows that well-being depends on multidimensional configurations of temperament and character traits (i.e., Joint Personality Networks) that regulate the way people learn t

TSH receptor antibodies (TRAb) – A potential new biomarker for endometriosis

Objectives: The prevalence of several autoimmune diseases, including thyroid dysfunction, has been reported to be increased in patients with endometriosis. Upregulated thyroid stimulation hormone (TSH) receptors in ectopic endometrium and elevated serum titers of TSH receptor antibodies (TRAb) IgG in endometriosis patients indicates an overlap in pathophysiology. However, cross-reactivity with oth

The development of a multidimensional meaning of tax: From unfair tax to fair

Historically, companies have communicated taxes as a burden, as the benefits provided by governments are not perceived to be in proportion to their payments. With sustainable development becoming central in many policy areas, new discourses including ‘fair’ or ‘sustainable’ tax have become omnipresent in public talk on taxes. This paper analyzes tax discourses in corporate annual reports within thHistorically, companies have communicated taxes as a burden, as the benefits provided by governments are not perceived to be in proportion to their payments. With sustainable development becoming central in many policy areas, new discourses including ‘fair’ or ‘sustainable’ tax have become omnipresent in public talk on taxes. This paper analyzes tax discourses in corporate annual reports within th

“The People’s Park is bigger, more freely located, more beautiful and – Our own park”: Workers, parks, and the spaces of class struggle in turn of the century Norrköping, Sweden. Environment

Engaging with scholarship on hegemony, park history, and in particular with Sevilla-Buitrago’s analysis of Central Park as a pedagogical space, this article traces the establishment of two parks in the Swedish textile industry centre of Norrköping. These parks, bearing very similar names – Folkparken and Folkets Park – were established just six years apart. But though both parks linked “park” and

Characteristics of SARS-CoV-2-containing aerosols in hospital corridors

The aim of this work is to investigate the presence of airborne SARS-CoV-2 in corridors of infection wards, and gain more detailed size information of SARS-CoV-2-containing aerosols. Associations between SARS-CoV-2 presence and relative humidity and/or temperature in the facilities is also explored.

Purposeful combination : Management of Knowledge Integration in the Development of Self-Driving Cars

See English version.Se engelsk version.Knowledge integration theory frames outputs of firm activity as a combination of multiple individuals’ knowledge. Previous research have greatly advanced our understanding of the management of knowledge integration by exploring the influence of various problem characteristics. This study attempts to contribute to an alternative, more strategic, approach in which knowledge integration is treated as