Sökresultat

Many bacteria can interfere with how antibodies bind to their surfaces. This bacterial antibody targeting makes it challenging to predict the immunological function of bacteria-associated antibodies. The M and M-like proteins of group A streptococci (GAS) exhibit IgGFc-binding regions, which they use to reverse IgG binding orientation depending on the host environment. Unraveling the mechanism beh

Glucagon is secreted from the pancreatic alpha cells and plays an important role in the maintenance of glucose homeostasis, by interacting with insulin. The plasma glucose levels determine whether glucagon secretion or insulin secretion is activated or inhibited. Despite its relevance, some aspects of glucagon secretion and kinetics remain unclear. To gain insight into this, we aimed to develop a

Understanding the origin of chondritic components and their accretion pathways is critical to unraveling the magnitude of mass transport in the protoplanetary disk, as well as the accretionary history of the terrestrial planet region and, by extension, its prebiotic inventory. Here we trace the heritage of pristine components from the relatively unaltered CV chondrite Leoville through their mass-i

Spatial variation in community composition may be driven by a variety of processes, including environmental filtering and dispersal limitation. While work has been conducted on the relative importance of these processes on various taxa and at varying resolutions, tests using high-resolution empirical data across large spatial extents are sparse. Here, we use a dataset on the presence/absence of br

AIMS: Patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) have increased prevalence of atrial arrhythmias indicating atrial involvement in the disease. We aimed to assess the long-term evolution of P-wave indices as electrocardiographic (ECG) markers of atrial substrate during ARVC progression. METHODS AND RESULTS: We included 100 patients with a definite ARVC diagnosis according

Introduction.Streptococcus dysgalactiae subspecies equisimilis (SDSE) is becoming increasingly recognized as an important human pathogen. Recurrent bacteremia with SDSE has been described previously.Aim. The aims of the study were to establish the genetic relatedness of SDSE isolates with emm-type stG643 that had caused recurrent bacteraemia in three patients and to search for signs of horizontal

The loss of long-tongued pollinator species and dominance of a few short-tongued generalist species, related to agricultural intensification in recent decades, may have consequences for the quality, quantity, and stability of yields in insect-pollinated crops. Interestingly, the changes in pollinator community coincide with an increase in poor and variable seed yield in red clover, an important cr

This study highlights the need to increase our understanding of the interplay between sensor drift and the performance of the automatic control system. The impact from biased sensors on the automatic control systems is rarely considered when different control strategies are assessed in water resource recovery facilities. Still, the harsh measurement environment with negative effects on sensor data

The emergent patterns of collective motion are thought to arise from application of individual-level rules that govern how individuals adjust their velocity as a function of the relative position and behaviours of their neighbours. Empirical studies have sought to determine such rules of interaction applied by 'average' individuals by aggregating data from multiple individuals across multiple traj

Observations and studies of what we call magnetic induced transitions have arguably re-opened a whole new area of atomic spectroscopy. There are transitions from upper levels that are sensitive to externally applied magnetic fields, such as those in tokamaks and the solar corona. So far only two types of ionic systems have been confirmed as leading to magnetic induced transitions, namely Ne-like A

Lung cancer (LC) generally lacks unique core symptoms or signs. However, there are a multitude of bodily sensations that are often non-specific, not easily understood, and many times initially not recognized as indicative of LC by the affected person, which often leads to late diagnosis. In this international qualitative study, we inductively analyzed retrospective accounts of 61 people diagnosed

The upgrade of the ALICE TPC will allow the experiment to cope with the high interaction rates foreseen for the forthcoming Run 3 and Run 4 at the CERN LHC. In this article, we describe the design of new readout chambers and front-end electronics, which are driven by the goals of the experiment. Gas Electron Multiplier (GEM) detectors arranged in stacks containing four GEMs each, and continuous re

Catalysts are materials that accelerate the rate of a desired chemical reaction. As such, they constitute an integral part in many applications ranging from the production of fine chemicals in chemical industry to exhaust gas treatment in vehicles. Accordingly, it is of utmost economic interest to improve catalyst efficiency and performance, which requires an understanding of the interplay between

We replicate the Wiklund et al. (2003) study examining the attitudes towards growth of small business managers. We generalize and extend that study in three important ways: we focus on a different context (United States instead of Sweden), where the conditions and consequences for growth are different, we provide an additional predictor variable – behavioral control – in line with Ajzen’s theory o

Climate change models predict an increase in the intensity and frequency of drought periods as well as precipitation events. Moisture and its fluctuations have a large impact on soil microorganisms, which are key drivers of the terrestrial carbon (C) cycle. When there is a drought period followed by a rainfall event there is a big CO2 release from soil to the atmosphere, which can dominate the C b

This paper describes a measurement of light-by-light scattering based on Pb+Pb collision data recorded by the ATLAS experiment during Run 2 of the LHC. The study uses 2.2 nb−1 of integrated luminosity collected in 2015 and 2018 at sNN = 5.02 TeV. Light-by-light scattering candidates are selected in events with two photons produced exclusively, each with transverse energy ETγ> 2.5 GeV, pseudorapidi