Activation of AMP-activated protein kinase (AMPK) is considered an attractive strategy for the treatment of type 2 diabetes. Favorable metabolic effects of AMPK activation are mainly observed in skeletal muscle and liver tissue whereas the effects in human adipose tissue are only poorly understood. Previous studies, which largely employed the AMPK activator 5-aminoimidazole-4-carboxamide-1-D-ribof

Population-based data on metastatic patterns are lacking because cancer registries seldom record metastases. This study uses a novel population-based approach to identify metastases and describes metastatic pathways from 14 common primary cancers to 12 specific metastatic sites. A total of 179 581 patients with metastatic cancer were identified from the Swedish Cancer Registry and metastatic sites

This paper examines the social rules and conventions of photography practices on visual social media platforms through revisiting the concept of gaze. More specifically we analyse how 25 participants in so-called Instagram take-overs make sense of and perform photography as an embodied visual practice situated in time and space. Hence, approaching that which is seen on Instagram from the viewpoint

Visuals like photographs and videos produced and circulated by lay people in social media serve as significant mediators in crisis communication. Such visuals are crucial for the way contemporary crisis events are defined and perceived in public (Mortensen, 2015; Coombs, 2007). This type of eyewitness footage is a growing visual genre of crisis communication. Yet, previous studies tend to neglect

Water-butanol and water-hexane flows were visualized in ultra-shallow straight and serpentine microchannels with a cross-junction. At the inlet cross-junction, three major flow patterns including tubing/threading, dripping and jetting were mapped using the aqueous Capillary number versus the organic Weber number. Correspondingly, in the main microchannel, annular flow, slug flow and droplet flow w

Molten-salt-based nanofluids and ionic-liquid-based nanofluids are developed for thermal storage and heat transfer at relatively high temperatures, in the past few years. Preparation and stabilization techniques are briefly introduced firstly, and then, thermal properties, e.g., specific heat, thermal conductivity and viscosity, are summarized and discussed in detail. The properties are not only a

This chapter presents a state-of-the-art overview of numerical methods for single-phase flow and two-phase flow in microchannel heat exchangers, as well as the relevant single-phase and two-phase computational fluid dynamics (CFD) applications. Governing equations are given for both single-phase flow and two-phase flow with and without phase change. For single- phase flow, scaling effects, such as

An experimental investigation was performed for convective condensation of R410A inside four micro-fin tubes with the same outside diameter (OD) 5 mm and helix angle 18°. Data are for mass fluxes ranging from about 180 to 650 kg/m2s. The nominal saturation temperature is 320 K, with inlet and outlet qualities of 0.8 and 0.1, respectively. The results suggest that Tube 4 has the best thermal perfor

This paper verified the macro-to-micro-scale transitional criterion BoRel 0.5 = 200 proposed by Li and Wu [W. Li, Z. Wu, A general criterion for evaporative heat transfer in micro/minichannels, International Journal of Heat and Mass Transfer 53 (2010) 1967-1976] because data points where BoRel 0.5 ≤ 200 and BoRel 0.5 > 200 show very different trends for the entire database (1,672 data points). For

Hydropower is a major energy source in Sweden, and proper reservoir management prior to the spring-flood onset is crucial for optimal production. This requires accurate forecasts of the accumulated discharge in the spring-flood period (i.e. the spring-flood volume, SFV). Today's SFV forecasts are generated using a model-based climatological ensemble approach, where time series of precipitation and

OBJECTIVE: To describe the clinical and ultrasound characteristics of ovarian pure endometrioid carcinomas.METHODS: This was a retrospective multicenter study of patients with a histological diagnosis of pure endometrioid carcinoma. We identified 161 patients from the International Ovarian Tumor Analysis (IOTA) database who had undergone preoperative ultrasound examination by an experienced ultras

Agriculture is vulnerable to the interannual climate variability and to its unpredictability, in such a way that most agricultural decisions taken within the time horizon of several months are made in a conservative manner, supposing a near-pessimist scenario. The improvement of climate prediction may help the strategic view, mitigating unwanted impacts and taking advantage of favorable conditions

Statistical atmospheric rainfall downscaling, that is, statistical estimation of local or regional rainfall on the basis of large-scale atmospheric circulation, has been advocated to make the output from global and regional climate models more accurate for a particular location or basin. Neural networks (NNs) have been used for such downscaling, but their application has proved problematic, mainly