Secretion of pancreatic lipase and colipase from rat pancreas.
Rat pancreatic juice was collected from female, anesthetized Sprague-Dawley rats (200–250 g) during basal secretion and after 45-min intravenous infusion for secretin or secretin with cholecystokinin (CCK). The volume of secretion was measured as well as activity of lipase and colipase. It was shown that the basal secretion of pancreatic juice gave a colipase/lipase (C/L) ratio of about 0.5. Stimu