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Perspective: multi-configurational methods in bio-inorganic chemistry

Transition metal ions play crucial roles in the structure and function of numerous proteins, contributing to essential biological processes such as catalysis, electron transfer, and oxygen binding. However, accurately modeling the electronic structure and properties of metalloproteins poses significant challenges due to the complex nature of their electronic configurations and strong correlation e

The sPHENIX Micromegas Outer Tracker

The sPHENIX Time Projection Chamber Outer Tracker (TPOT) is a Micromegas based detector. It is a part of the sPHENIX experiment that aims to facilitate the calibration of the Time Projection Chamber, in particular the correction of the time-averaged and beam-induced distortions of the electron drift. This paper describes the detector mission, setup, construction, installation, commissioning and pe

High resolution Ordovician carbon isotope chemostratigraphy in South China and its significance for global correlation

Based on the Shidi-1 drill core, this paper presents new and highly time resolved carbon isotope data (δ13Ccarb) for the Early Ordovician through Early Silurian of the Yangtze Platform, South China. Five carbon isotopic shifts (C1-C5) through the late Tremadocian to the Katian have been recognized in the Shidi-1 drill core recordings. Together with previously published isotope data, a composite ca

Synthesis of 2-acetamido-2-deoxy-3-O-β-d-galactopyrano-syl-d-galactose by the sequential use of β-d-galactosidases from bovine testes and escherichia coli

β-d-Galp-(1→3)-d-GalNAc (1) was synthesised from lactose and GalNAc on a mmolar scale by transgalactosylation using β-d-galactosidase from bovine testes. The large proportions of unwanted oligosaccharides in the product mixture were removed by treatment with β-d-galactosidase from E. coli, which left 1, monosaccharides, and a small proportion of trisaccharides. Carbon-Celite chromatography then ga

Simulation-based consequence analysis of reinforced-concrete buildings subjected to earthquake- and environment-induced damage accumulation

Structural systems in seismic-prone regions can experience sudden deterioration caused by earthquake-induced ground-motion sequences. In addition, given the prevailing environmental conditions at their site, these systems may undergo gradual deterioration resulting from environment-induced mechanisms. The combined impacts of such phenomena can result in significant structural/non-structural damage

Modeling deterioration and predicting remaining useful life using stochastic differential equations

The deterioration of engineering systems might reduce the system reliability and prompt maintenance operations that may disrupt the ability of the systems to provide regular service. Estimating the Remaining Useful Life (RUL) of the system requires an understanding of the deterioration processes acting on it. Recent formulations have shifted the focus of deterioration modeling from the system as a

Dynamics of Aedes aegypti mating behaviour

The use of pheromones, while common, remains underexplored in mosquito research. Understanding Aedes aegypti's mating behaviour and pheromones is crucial for expanding knowledge and advancing vector control strategies. Unlike other species, Aedes mosquitoes have adaptable mating behaviour, complicating the study of their communication mechanisms. Current literature on Aedes communication is sparse

Studies of the reversed α-mannosidase reaction in high concentrations of mannose

The reversal of the hydrolytic activity of α-mannosidase from jack bean has been studied in high concentrations of mannose. From an initial concentration of 85% mannose (w/w), a maximum yield of 70% (w/w) di- and oligosaccharides was obtained. The products were separated by gel chromatography and high-performance liquid chromatography, and characterized by gas-liquid chromatographymass spectrometr

Synthesis of Galβ1-3GlcNAc and Galβ1-3GlcNAcβ-SEt by an enzymatic method comprising the sequential use of β-galactosidases from bovine testes and Escherichia coli

Galβ1-3GlcNAc (1) and Galβ1-3GlcNAcβ-SEt (2) were synthesized on a 100 mg scale by the transgalactosylation reaction of bovine testes β-galactosidase with lactose as donor andN-acetylglucosamine and GlcNAcβ-SEt as acceptors. In both cases the product mixtures contained unwanted isomers and were treated with β-galactosidase from Escherichia coli which has a different specificity, under conditions f

Punishment Moralism

In this paper, I try to reconcile the vulgar (normative) definition of punishment with the positivistic (purely descriptive) definition that separates the ethics of punishment from its definition—punishment positivism. I will argue that although the vulgar definition has critical issues, this does not mean that we should stop using normative concepts in the definition of punishment. I will attempt

Animal Bones From Iron Age Settlements in Scania, Southern Sweden : A Database From the Sheep Ahoy Project

This paper presents the data constituting the catalogue of animal bones from Iron Age settlements in Scania, as published in the book “Animal husbandry in Iron Age Scania, with a catalogue”, and part of the Sheep Ahoy project at Lund University. The dataset consists of osteological data from zooarchaeologically examined animal bone assemblages from Iron Age settlement sites in Scania. The data has

Ett nytt verktyg för nya tider - en analys av dubbel markanvisning på Gotland

This bachelor thesis uses the case of a double land allocation agreement on the Swedish island of Gotland and asks to what degree neoliberal planning is present when using the policy instrument. The main theoretical framework used was that of David Harvey(2005), on the manifestation of neoliberal policies. His framework puts forth four main ways in which neoliberal policies are manifested. In orde

Preventive cognitive protection based on AAV9 overexpression of IGF1 in hippocampal astrocytes

Astrocytes play key roles in the brain. When astrocyte support fails, neurological disorders follow, resulting in disrupted synaptic communication, neuronal degeneration, and cell death. We posit that astrocytes overexpressing neurotrophic factors, such as Insulin Like Growth Factor 1 (IGF1), prevent the onset of neurodegeneration. We overexpressed IGF1 and the reporter TdTomato (TOM) in hippocamp

Search for charged-lepton-flavor violating Formula Presented interactions in top-quark production and decay in Formula Presented collisions at Formula Presented with the ATLAS detector at the LHC

A search for charged-lepton-flavor violating Formula Presented (Formula Presented, Formula Presented) interactions is presented, considering both top-quark production and decay. The data analyzed correspond to Formula Presented of proton-proton collisions at a center-of-mass energy of Formula Presented recorded with the ATLAS detector at the Large Hadron Collider. The analysis targets events conta

Experimental and kinetic modelling study on the laminar burning velocities of ultra-lean n-heptane flames at atmospheric pressure

Ultra-lean combustion is a promising strategy for enhancing engine efficiency and reducing pollutant emissions. In the present study, laminar burning velocity, SL, of n-heptane, a key gasoline surrogate component, was measured at 298 K and 1 atm using the heat flux method. The experimental conditions cover ultra-lean conditions with an equivalence ratio as low as 0.5 that have never been reported

Probing the strength of radial migration via churning by using metal-rich red giant stars from APOGEE

Making use of the APOGEE DR17 catalogue with high quality data for 143 509 red giant branch stars we explore the strength of different mechanisms that causes a star to radially migrate in the Milky Way stellar disc. At any position in the disc we find stars that are more metal-rich than the local interstellar medium. This is surprising and normally attributed to the migration of these stars after

Hall Algebras

Matematiker undersöker ofta talsystem som är annorlunda från de vanliga talen vi är vana vid. Ett exempel på ett sådant talsystem är timmarna på en klocka, där 13 = 1 och 9 + 6 = 3. Ett mindre självklart exempel är sekvenser av drag på en Rubik's kub. Man kan addera ihop två dragsekvenser genom att göra dem efter varandra, och det går att göra algebraiska manipulationer med dessa drag precis sThis thesis uses the strategy of Dyckerhoff-Kapranov to show the associativity and unitality of Hall Algebras for proto-abelian categories. After a more classical introduction to Hall algebras, we show that the Waldhausen S-construction of a proto-abelian category is a 2-Segal simplicial groupoid, and use this to construct a monoid object in the category of spans in groupoids. We then use this mon