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Phthalate diesters and their metabolites in human breast milk, blood or serum, and urine as biomarkers of exposure in vulnerable populations

BACKGROUND: Phthalates may pose a risk for perinatal developmental effects. An important question relates to the choice of suitable biological matrices for assessing exposure during this period. OBJECTIVES: This study was designed to measure the concentrations of phthalate diesters or their metabolites in breast milk, blood or serum, and urine and to evaluate their suitability for assessing perina

Serum Estradiol Levels Are Inversely Associated With Cortical Porosity in Older Men

Context: The key role of serum estradiol (E2) for bone health in men is well established. The effect of serum sex steroids on bone microstructure, measured by high-resolution peripheral quantitative computed tomography, remains unknown in elderly men. Objective: The objective of the study was to examine the associations between serum sex steroids and bone microstructural parameters in older men. M

Connecting hygroscopic growth at high humidities to cloud activation for different particle types

This work recompiles studies that have been done with respect to hygroscopic growth in the regime of high relative humidities and with respect to activation for different kinds of particle at LACIS (Leipzig Aerosol Cloud Interaction Simulator) during the last few years. The particles examined consisted of a mixture of succinic acid and ammonium sulfate, seawater samples, soot coated with an organi

A process for the production of ectoine and poly(3-hydroxybutyrate) by Halomonas boliviensis.

The paper reports a study involving the use of Halomonas boliviensis, a moderate halophile, for co-production of compatible solute ectoine and biopolyester poly(3-hydroxybutyrate) (PHB) in a process comprising two fed-batch cultures. Initial investigations on the growth of the organism in a medium with varying NaCl concentrations showed the highest level of intracellular accumulation of ectoine (0

Prolate shape of Ba-140 from a first combined Doppler-shift and Coulomb-excitation measurement at the REX-ISOLDE facility

Background: Quadrupole moments of excited nuclear states are important observables for geometrically interpreting nuclear structure in terms of deformed shapes, although data are scarce and sometimes ambiguous, in particular, in neutron-rich nuclides. Purpose: A measurement was performed for determining the spectroscopic quadrupole moment of the 2(1)(+) state of Ba-140 in order to clarify the char

Functional Studies of microRNAs in Neural Stem Cells : Problems and Perspectives

In adult mammals, neural stem cells (NSCs) are found in two niches of the brain; the subventricular zone by the lateral ventricles and the subgranular zone of the dentate gyrus in the hippocampus. Neurogenesis is a complex process that is tightly controlled on a molecular level. Recently, microRNAs (miRNAs) have been implicated to play a central role in the regulation of NCSs. miRNAs are small, en

J/psi suppression at forward rapidity in Au plus Au collisions at root s(NN)=200 GeV

Heavy quarkonia are observed to be suppressed in relativistic heavy-ion collisions relative to their production in p + p collisions scaled by the number of binary collisions. In order to determine if this suppression is related to color screening of these states in the produced medium, one needs to account for other nuclear modifications including those in cold nuclear matter. In this paper, we pr

Atenolol in the prophylaxis of chronic migraine: a 3-month open-label study.

Chronic migraine (CM) is a type of chronic daily headache. CM presents a challenge to primary care physicians and neurologists. Any new treatment showing efficiency would therefore be of great importance. Atenolol together with other beta-blockers is a first-line choice in episodic migraine prophylaxis. Clinical findings support the efficacy of atenolol in doses of 50 to 200 mg/day.

Decoding of individuated finger movements using surface EMG and input optimization applying a genetic algorithm.

In this paper we present surface electromyographic (EMG) data collected from 16 channels on five unimpaired subjects and one transradial amputee performing 12 individual finger movements and a rest class. EMG were processed using a traditional Time Domain feature-set and classifiers: a Linear Discriminant Analysis (LDA) a k-Nearest Neighbors (k-NN) and Support Vector Machine (SVM). Using continuou

The Association between HIV Infection, Antiretroviral Therapy and Cervical Squamous Intraepithelial Lesions in South Western Nigerian Women.

Findings from studies that evaluated the effect of antiretroviral drug use on the development of cervical squamous intraepithelial lesion differed in their conclusions. This study investigated the association between HIV infection, antiretroviral drug use and cervical squamous intraepithelial lesion in a high HIV and cervical cancer burden setting- Nigeria.

Experimental and numerical studies of creasing of paperboard

A laboratory creasing device to capture the most important properties of a commercial rotary creasing tool was designed. Finite element analysis of the creasing of a multiply paperboard in the laboratory crease device was presented. The multiply paperboard was modeled as a multilayered structure with cohesive softening interface model connecting the paperboard plies. The paperboard plies were mode

Measurements of the electron and muon inclusive cross-sections in proton-proton collisions at root s=7 TeV with the ATLAS detector

This Letter presents measurements of the differential cross-sections for inclusive electron and muon production in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV, using data collected by the ATLAS detector at the LHC. The muon cross-section is measured as a function of p(T) in the range 4 < p(T) < 100 GeV and within pseudorapidity vertical bar eta vertical bar < 2.5. In addi

What limits the pedestrian? Exploring perceptions of walking in the built environment and in the context of every-day life

Walkability is often researched from the perspective of certain physical features in the built environment. However, for this paper, the point of departure was to also treat walking as a transport mode for reaching destinations and performing every-day activities. A conceptual model addressing both perceptions of the built environment and perceived limits due to every-day activities was used as a

Virtual Multi-link Propagation Investigation of an Outdoor Scenario At 300 MHz

The COST 2100 channel model has introduced the concept of common clusters to model multi-link MIMO characteristics. In this paper, a ray launching tool is used to analyze multi-ink propagation properties in an outdoor scenario at 300 MHz. It is shown that in a multi-link propagation scenario there are shared scatterers among the different links, which reflects the physical existence of common clus

A Peptide of Heparin Cofactor II Inhibits Endotoxin-Mediated Shock and Invasive Pseudomonas aeruginosa Infection.

Sepsis and septic shock remain important medical problems with high mortality rates. Today's treatment is based mainly on using antibiotics to target the bacteria, without addressing the systemic inflammatory response, which is a major contributor to mortality in sepsis. Therefore, novel treatment options are urgently needed to counteract these complex sepsis pathologies. Heparin cofactor II (HCII