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Co-injection of anti-HER2 antibody Trastuzumab does not increase efficacy of [177Lu]Lu-PSMA-617 therapy in an animal model of prostate cancer
One novel option for treating metastatic castration resistant prostate cancer is radionuclide therapy targeting prostate-specific membrane antigen (PSMA), e.g. [177Lu]Lu-PSMA-617. Overexpression of HER2 has been found in 80% of metastatic cases of prostate cancer. Previous research showed that HER2 is elevated post irradiation in PC-3 prostate cancer cells. Co-treating with anti-HER2 antibody Tras
Det hälsosamma
Bilder i språket - om alternativa uttryckssätt
Skick och bruk på läkarmottagningen
The sociological nature of competition as viewed from the grocery shop floor in Sweden
Lyxsyssla blev folkrörelse : Svensk fritidsbåtskultur
Många båtentusiaster skriver under på den romerske fältherren Pompejus bevingade ord navigare necesse est, att segla är nödvändigt. Länge var nöjessjöfarten i svenska farvatten dock förbehållen en privilegierad elit, ända tills fritidsbåtsmodeller, för segel och motor, utvecklades
Maktens subtilitet
Rapid Profiling of Protein Complex Reorganization in Perturbed Systems
Protein complexes constitute the primary functional modules of cellular activity. To respond to perturbations, complexes undergo changes in their abundance, subunit composition, or state of modification. Understanding the function of biological systems requires global strategies to capture this contextual state information. Methods based on cofractionation paired with mass spectrometry have demons
Closing Data Gaps and Paving the Way for Pan-European Fire Safety Efforts : Part II—Terminology of Fire Statistical Variables
A well-defined terminology of fire-related variables is important for correct analyses and supporting knowledge-based decisions regarding the evaluation of building fires at the European level. After developing an overview of current practices for fire statistics in Part I, the terminology used and the data collected by the EU Member States and eight other countries regarding fire incidents, prope
Context-dependent insect predation pressure on an avian ectoparasite
Context dependence arises when ecological relationships vary with the conditions under which they are observed. Context dependence of interactions involving parasites is poorly known, even if it is key to understanding host–parasite relationships and food web dynamics. This paper investigates to which extent predation pressure on an avian ectoparasite (Carnus hemapterus) is context-dependent. Base
Case report : Bilateral damage to the immature optic radiation and secondary massive loss of retinal ganglion cells causing tunnel vision
We describe the case of a 30-year-old woman, who needed a formal report on her visual impairment to seek support from society. She was born preterm, and during her neonatal period, she suffered from bilateral intraventricular hemorrhage (IVH) grade 3, a condition that can cause cerebral visual impairment (CVI) due to damage to the retro-geniculate visual pathways. Individuals with such brain damag
Expressivity within a time schedule: subordinated interaction on geriatric wards
Room temperature X-ray absorption spectroscopy of metalloenzymes with drop-on-demand sample delivery at XFELs
X-ray crystallography and X-ray spectroscopy using X-ray free electron lasers plays an important role in understanding the interplay of structural changes in the protein and the chemical changes at the metal active site of metalloenzymes through their catalytic cycles. As a part of such an effort, we report here our recent development of methods for X-ray absorption spectroscopy (XAS) at XFELs to
Långvården och en sociologisk klassiker
Tid och maktkamp
Recension av Reidun Norvoll: Det lukkede rom. Bruk av skjerming som behandling og kontroll i psykiatriske akuttposter, Avhandling för sosiologi og samfunnsgeografi, Universitetet i Oslo 2007
Resisting the epistemic argument for compatibilism
In this paper, we clarify, unpack, and ultimately resist what is perhaps the most prominent argument for the compatibility of free will and determinism: the epistemic argument for compatibilism. We focus on one such argument as articulated by David Lewis: (i) we know we are free, (ii) for all we know everything is predetermined, (iii) if we know we are free but for all we know everything is predet