BACKGROUND: The Eight-Twenty-One (ETO) nuclear co-repressor gene belongs to the ETO homologue family also containing Myeloid Translocation Gene on chromosome 16 (MTG16) and myeloid translocation Gene-Related protein 1 (MTGR1). By chromosomal translocations ETO and MTG16 become parts of fusion proteins characteristic of morphological variants of acute myeloid leukemia. Normal functions of ETO homol

In this manuscript, a new strategy has been reported for circumscribed covalent attachment of barbed and pointed ends of actin filaments to polystyrene beads. A comparative study of attachment of actin filaments to polystyrene beads was performed by blocking functionally active sites on polystyrene beads with nonionic detergents such as Tween 20, Tween 80 and polyethylene glycol (PEG). Effective b

In the present manuscript, we report the studies and observations for chemical interference due to aggregates formation during covalent immobilization of thiolated lambda-DNA between gold microelectrodes. Dip and Drop approaches were employed to study DNA immobilization using thiolated oligos (oligoA 5' GGGCGGCGACCT 3' and oligoB 5' AGGTCGCCGCCC 3'). As a result of aggregation, less interference w

The project combines the highly sensitive salt(NaCl) dosemeter for photon radiation with a neutronphotonconverter in the form of thin gadolinium foilsenclosing the salt. Using an identical salt dosemeter butwithout gadolinium cover determines the primaryphoton contribution. With these twin dosemeters placedin a polyethylene sphere, both photon and neutron dosecontributions can be estimated. This p

This introductory chapter gives an overview of the intricate relation between Heidegger and theology. Firstly, it discusses Heidegger’s indebtedness to theology by revisiting the debate that was initiated by the publication of his early Freiburg lectures in the 1990s. Second, it sketches in broad strokes the reception history of Heidegger’s works within twentieth century theology. In the third and

Due to the significant increase in pediatric trunk computed tomography (CT) examinations, there is a need for a reliable approach of conducting effectivedose estimate for such procedures. The current study is based on two dosimetric anthropomorphic phantoms representing a 1-year and a 5-year old child. Effectiveand equivalent tissue doses from CT examinations of the trunk were determined by thermo

One of the intensively explored domains of the current bionanotechnology is the focus for search of nano-materials intended to develop high throughput electronic devices. Among the questioned physical materials deoxyribonucleic acid (DNA) has given promising background to be explored as potential nanowire material for aspiring nano-devices. The distinguished characteristics of electron hopping bet

Transfer integrals for oligos with different bases have been calculated using INDO/Koopman's approximation to unveil the charge transport mechanism in DNA. The sequences, G(A)nG, n = 1, 2, …, 10; G(A)xG(A)yG, x + y = 9; and G(A)xG(A)yG(A)zG, x + y + z = 8, were employed to interpret the Guanine (G) and Adenine(A) hopping. Adenine hopping is found to be faster in G(A)nG sequences with longer Adenin

Optically stimulated luminescence (OSL) from ordinary household salt has proven high potential for very low dose retrospective dosimetry. In the present paper other common place materials are considered and their dosimetric OSL-properties compared with household salt. The potential for assessment of the effective dose to an individual carrying such materials is investigated.

Having previously demonstrated that in-patients referred to neurology at two UK hospitals were not fully examined prior to referral, we designed an audit with 80% power to detect a 10% increase in tendon hammer or ophthalmoscope use following an educational intervention. In-patients referred to neurology over a 4 month period in the UK, Jordan, Sweden and the United Arab Emirates were asked whethe

Establishing diagnostic reference levels (DRLs) in a big country is complicated due to differences in radiological practice between different regions. In 2009-2014, a dose survey was performed in six Russian regions. Based on the results of the survey, preliminary DRLs for conventional X-ray examinations were established on a national level. Additionally, the local authorities were granted the pos

Covalent attachment of biomolecules to the surface of carbon nanotubes provides an architecture for three dimensional arrays of sensor molecules (i.e. enzymes) for potential biosensor application. Present work reports a simple two-step reaction for immobilization of glucose oxidase on single walled carbon nanotubes (SWCNTs). This method is as efficient as conventional methods for biofunctionalizat

In the present manuscript, current-voltage (I-V) measurements of double stranded guanine rich sequences of λ-DNA have been reported. These sequences show length dependent conductivity. Conductivity (σ0) DNA of length, L = 0.6494 x 10-4 (1910 bp), 1 x 10-4 (2947 bp) and 1.3498 x 10-4 cm (3970 bp) was found to be 2.4 x 105, 7.7 x 102 Ω-1cm-1 and insulator behavior, respectively. I-V characterization

Aims: To illustrate the importance of access to register data on determinants and predictors of study participation to assess validity of population-based studies. In the present investigation, we use data on sociodemographic conditions and disease history among individuals invited to the Swedish cardiopulmonary bio-image study (SCAPIS) in order to establish a model that predicts study participati

Global health diplomacy (GHD) focuses on international negotiation; principally between nation states, but increasingly non-state actors However, agreements made at the global level have to be enacted at the national, and in some cases the sub-national level. This presents two related problems: (1) how can success be measured in global health diplomacy and (2) at what point should success be evalu

Complex security environments are characterized by violence (including, but not limited to "armed conflict" in the legal sense), poverty, environmental disasters and poor governance. Violence directly affecting health service delivery in complex security environments includes attacks on individuals (e.g. doctors, nurses, administrators, security guards, ambulance drivers and translators), obstruct

BACKGROUND: Previous analyses concerning health components of European Union (EU)-funded research have shown low project participation levels of the 12 newest member states (EU-12). Additionally, there has been a lack of subject-area analysis. In the Health Research for Europe project, we screened all projects of the EU's Framework Programmes for research FP5 and FP6 (1998-2006) to identify health