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Direct activation of a bacterial innate immune system by a viral capsid protein

Bacteria have evolved diverse immunity mechanisms to protect themselves against the constant onslaught of bacteriophages1-3. Similar to how eukaryotic innate immune systems sense foreign invaders through pathogen-associated molecular patterns4 (PAMPs), many bacterial immune systems that respond to bacteriophage infection require phage-specific triggers to be activated. However, the identities of s

Extending relativistic linear response theory to address solvent effects

The central aim of this thesis is to derive, implement and test new methods to calculate various types of spectroscopies of compounds containing heavy elements in an aqueous environment. Methods that can target such systems have to consider the following:(i) It is crucial to take relativistic effects into account.(ii) Modeling of larger systems is expensive in quantum chemistry. Thus, cheaper opti

Collective collapse in football

Collective collapse occurs when a majority of the players in a team suddenly perform below expected level in a match, in spite of a satisfactory start, or when a team underperforms right from the start. Research results from a study on 146 male players and 15 coaches in various team sports at the elite level, and a study on a team involved in a collective collapse, and the opposite, a winning turn

Accomplishing Reality Media : The Affective Lure of Online Crime Discussions

Drawing from interviews with posters and an analysis of a dozen discussion threads on the Swedish online discussion forum Flashback, this article sets out to investigate the dramatization of crime news from the point of view of the participants themselves. Analyzing both the online discussions and the articulated motivations and activities of the posters, this article focuses on how participants i

First Record of Microsporidia Infection in the Damselfly Ischnura elegans Larvae : Temperature and Predator Cue Effects on the Host’s Life History

Here, we report, for the first time, a microsporidian infection in laboratory-reared larvae of the damselfly Ischnura elegans. Infected larvae originated from field-collected adult females, which were caught in southern Poland in August 2020 (the second half of the flight season). Higher rearing temperatures and the presence of predator cues from the invasive alien signal crayfish (Pacifastacus le

Fire behavior of sandwich panels

One of the most recent definitions for a sandwich panel is the one used in the European product standard EN 14509. This product standard defines a sandwich panel as a building product consisting of two metal faces positioned on either side of a core that is a rigid thermally insulating material, which is firmly bonded to both faces so that the three components act compositely when under load. In m

Biology teachers’ collaborative experiences : benefits and difficulties in different contexts in relation to perceived value

Collaboration has the potential to strengthen both professional learning and well-being for teachers. However, it can also bring problematic aspects, such as increased workload and conflicts. The purpose of this study was to explore biology teachers’ experiences of collaboration to better understand how upper secondary school organisations can support teachers to obtain valuable collaborations. By

Efficient and Flexible First-Order Optimization Algorithms

Optimization problems occur in many areas in science and engineering. When the optimization problem at hand is of large-scale, the computational cost of the optimization algorithm is a main concern. First-order optimization algorithms—in which updates are performed using only gradient or subgradient of the objective function—have low per-iteration computational cost, which make them suitable for t

Dating Business Cycles in the United Kingdom, 1700–2010

This paper constructs a new chronology of the business cycle in the United Kingdom from 1700 on an annual basis and from 1920 on a quarterly basis to 2010. The new chronology points to several observations about the business cycle. First, the cycle has significantly increased in duration and amplitude over time. Second, contractions have become less frequent but are as persistent and costly as at

Paving the Road to Flex and Biomass : The Land Surface Carbon Constellation Study

Remote sensing observations of variables related to vegetation at microwave and optical/infrared wavelengths are presented over three regions in Europe in the Iberian peninsula, northern Finland and central Europe. They include the instrumented sites of Las Majadas, Sodankyla and Reusel. The final goal is to better constrain land carbon cycle models using the complementarities of vegetation optica

Study of the kinetics, mechanisms and catalysis activity of photo-electro degradation of organic pollutants via new neural network based methodology

A novel calculation methodology containing modeling and statistics was developed to assist the experimental process for the investigation of organics treatment process. A continuous-flow photo-electro treatment of Norfloxacin (NOR) was chosen as a target subject. The methodology is based on a new synergistic work of reaction energy calculation, full-scanned neural network (NN) simulation and new p

Evaluation of a multi-zone modelling concept for large volume buildings and tunnels

The multi-zone modelling concept could be a good alternative to two-zone modelling and CFD modelling for some situations when performing fire safety designs. However, few such models exist, and the evaluation of the concept is scarce. This paper is dedicated to study the multi-zone modelling concept and its usefulness in fire safety engineering by benchmarking it against experimental data and simu

The complexity of kidney disease and diagnosing it - Cystatin C, selective glomerular hypofiltration syndromes and proteome regulation

Estimation of kidney function is often part of daily clinical practice, mostly done by using the endogenous GFR-markers creatinine or cystatin C. A recommendation to use both markers in parallel in 2010 has resulted in new knowledge concerning the pathophysiology of kidney disorders by identification of a new set of kidney disorders, selective glomerular hypofiltration syndromes. These syndromes,

Multi-dimensional imaging : A tool to unravel material properties at the nanoscale

Optical microscopy has revolutionized the way we understand our world and has become a crucial tool in a range of disciplines such as biology, physics, chemistry, and material sciences. The development of new microscopy techniques has been capital to its success and wide applicability. A prominent example is the recent development of methods that allow imaging in three dimensions. This has been a

Ecosystem services for urban destination development : Potential for sustainability

This chapter addresses opportunities and challenges in urban planning by implementing the concept of ecosystem services in an urban tourism and destination development context. In analysing ecosystem services in urban tourism, we contribute to an emerging literature focusing on urban ecosystem services. An important research gap is also addressed; despite the importance of tourism for cities, ther