We have recently completed the largest GWAS on lung cancer including 29,266 cases and 56,450 controls of European descent. The goal of our study has been to integrate the complete GWAS results with a large-scale expression quantitative trait loci (eQTL) mapping study in human lung tissues (n = 1,038) to identify candidate causal genes for lung cancer. We performed transcriptome-wide association st

Background: In collaboration with United European Gastroenterology, the working group on ‘Harmonizing diagnosis and treatment of chronic pancreatitis across Europe’ (HaPanEU) developed European guidelines for the management of chronic pancreatitis using an evidence-based approach. Methods: Recommendations of multidisciplinary review groups based on systematic literature reviews to answer predefine

Review of a doctoral dissertation in film art (artistic research), consisting of a written treatise as well as a filmic work, by filmmaker Patrik Eriksson (Göteborgs universitet/Gothenburg University).Review of a doctoral dissertation in film art (artistic research), consisting of a written treatise as well as a filmic work, by filmmaker Patrik Eriksson (Göteborgs universitet/Gothenburg University).

Putin lever inte för evigt, men dagens Ryssland är uppbyggt kring Putin som ledaren. Sovjettidens så kallade ”kremlologi” – att omvärlden spekulerar och ibland försöker tyda tecken som inte finns – kan märkas även i dag. Det är väldigt svårt att föreställa sig Ryssland om fem år, både för ryssar och för andra, skriver Mi Lennhag, Östeuropaexpert vid Lunds universitet och Vilhelm Konnander, säkerhe

The Routledge Companion to Media and Tourism provides a comprehensive overview of the research into the convergence of media and tourism and specifically investigates the concept of mediatized tourism.This companion offers a holistic look at the relationship between media and tourism by drawing from a global range of contributions by scholars from disciplines across the humanities and social scien

The sFLASH project at DESY is an experiment to study direct seeding using a source based on the high-harmonic generation (HHG) process. In contrast to SASE, a seeded FEL exhibits greatly improved longitudinal coherence and higher shot-to-shot stability (both spectral and energetic). In addition, the output of the seeded FEL is intrinsically synchronized to the HHG drive laser, thus enabling pump-p

Since 2004 the free-electron laser FLASH at DESY has been operated in the Self-Amplified Stimulated Emission mode (SASE), delivering gigawatt pulses with wavelengths between 6.5 nm and 40 nm in the femtosecond domain. In 2009 DESY installed an additional radiofrequency module for controlling the phase space of the electron bunches that gives the possibility to generate bunches with high peak curre

Coherent harmonic generation can be obtained by means of frequency up-conversion of a high-power external laser focused into the first undulator of an optical klystron. The standard configuration is based on a single-pass device, where the seed laser is synchronized with an electron beam entering the first undulator of the optical klystron after being accelerated using a linear accelerator. As an

In the name of transparency and accountability, numbers and statistics have gained importance as indicators of quality, effectiveness and efficiency of welfare services such as social work. It has been argued that the requirements to formalise how and on what grounds decisions are made have undermined the professional autonomy and discretion of social workers. These requests have arguably also led

Thanks to an intensive technological effort in the framework of the EUFELE collaboration, the European FEL at ELETTRA was able to break the previous record for the shortest wavelength of an FEL oscillator. Novel solutions were adopted for multilayer mirrors to allow FEL operation in the wavelength region between 160 and 190 nm, which is one of the main targets of the project. The characteristics o

Organoids have extensive therapeutic potential and are increasingly opening up new avenues within regenerative medicine. However, their clinical application is greatly limited by the lack of effective GMP-compliant systems for organoid expansion in culture. Here, we envisage that the use of extracellular matrix (ECM) hydrogels derived from decellularized tissues (DT) can provide an environment cap

Swedish administrative law has not devoted much attention to the con-cepts of discretion or deference with respect to the administration. This is explained by the historically founded competence of administrative courts conducting a full review under the so-called administrative-judicial form of appeal. Here, the administrative court has the same decision-making competence as the deciding administ

Myxoinflammatory fibroblastic sarcoma (MIFS) has recurrent genetic features in the form of a translocation t(1;10)(p22-31;q24-25), BRAF gene fusions, and/or an amplicon in 3p11-12 including the VGLL3 gene. The breakpoints on chromosomes 1 and 10 in the t(1;10) cluster in or near the TGFBR3 and OGA genes, respectively. We here used a combination of deep sequencing of the genome (WGS), captured sequ