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Data Augmentation for Object Detection using Deep Reinforcement Learning

Data augmentation is a concept which is used to improve machine learning models for computer vision tasks. It is usually done by firstly, defining a set of functions which transforms images and secondly, applying a random selection of these functions on the images. Since the quality of training data is one of the, if not the most important factor to obtain a good model, this master thesis poses th

Predicting Navigational Patterns in Web Applications using Machine Learning Techniques

In large corporations, customer support is a costly service, and an area of constant optimization. Solutions to increase efficiency and decrease bottlenecks are constantly needed. One such bottleneck is support tool proficiency in a customer support organization where many different tools are used, and a potential solution is to let the tool guide the user as it is being used. This thesis explores

“Where to put the spare cash?” : Subprime urbanization and the geographies of the financial crisis in the Global South

This article investigates the geographies of subprime urbanization, and by extension, the displacement of 2007–08 financial crisis to the Global South. Previous research examined the formative ways that technological innovations enabled mortgages to deterritorialize and circulate on secondary markets. Less is known about how cities with underdeveloped financial systems and housing markets have bee

Recombinant factor IX Fc for the treatment of hemophilia B

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

Perceptions of surveillance with magnetic resonance imaging among women with a hereditary risk of breast cancer—A phenomenographic study

AimTo explore perceptions of annual surveillance with magnetic resonance imaging and perceptions of care during the examination among women with a hereditary risk of breast cancer.DesignPhenomenography.MethodsFourteen face-to-face interviews using a semi-structured interview guide were conducted among women undergoing surveillance in the southern region of Sweden. A seven-step phenomenographic ana

Association of systemic anticholinergic medication use and accelerated decrease in lung function in older adults

Older adults are frequently exposed to medicines with systemic anticholinergic properties, which are linked to increased risk of negative health outcomes. The association between systemic anticholinergics and lung function has not been reported. The aim of this study was to investigate if exposure to systemic anticholinergics influences lung function in older adults. Participants of the southernmo

A case study of SCADA implementation for small electrical producers in WideQuick

The escalating demand for electricity requires the deployment of reliable, secure, and efficient energy production methods. This master thesis explores the utilization of Supervisory Control and Data Acquisition (SCADA) systems in power plants to meet these requirements. The primary objective is to investigate the specific requirements for implementing a SCADA system in the power production sector

Recurrent implantation failure and inflammatory markers in serum and follicle fluid of women undergoing assisted reproduction

It has been shown previously that the immune system plays a role in implantation and embryo development. The objective was therefore to evaluate cytokine levels and Th1/Th2 ratio in women with recurrent implantation failure in this nested case-control study. Women with no implantation after ≥ 3 embryo transfers were included in the recurrent implantation failure group (n = 29) and were compared wi

Evolving therapies, neurocognitive outcomes, and functional independence in adult survivors of childhood glioma

Background: Treatment of childhood glioma has evolved to reduce radiotherapy exposure with the goal of limiting late toxicity. However, the associations between treatment changes and neurocognition, and the contribution of neurocognition and chronic health conditions to attainment of adult independence, remain unknown. Methods: Adult survivors of childhood glioma diagnosed in 1970-1999 in the Chil

Formulation factors affecting foam properties during vacuum foam-drying

This paper explores how vacuum foam-drying of a protein is influenced by formulation parameters by investigating the foam structure, physical properties of the foam, and the stability of the protein. Recombinant human bile salt-stimulated lipase was used as a model of a protein drug. The stability of the lipase was evaluated through activity measurements. Two disaccharides (sucrose and trehalose),

Nackas framtid - En riskanalys för gentrifiering i samband med tunnelbanetillgänglighet

The municipality of Nacka is undergoing major urban development and transformation which is part of the project [Nacka becomes a city] which includes new developments of housing, commercial property, and shopping areas aimed to make Nacka a city. The project is driven by the expansion of the Stockholm metro system which is getting extended to Nacka. Such major changes of an urban area in correlati

Samtal och Samråd: En studie av kommunikation i samrådsprocessen i en detaljplan

The consultation process in Swedish planning provides an opportunity for citizens to participate in the planning process. Yet the influence of the citizens is varied and their ability to interact with the planners and the developer can sometimes be problematic. Using Haberma’s theory of communicative action, this study analyzes the interactions between the planners, contractors and citizens in the

Epidermal ET-1 signal induces activation of resting hair follicles by upregulating the PI3K/AKT pathway in the dermis

The prevalence of alopecia has increased recently. Hair loss is often accompanied by the resting phase of hair follicles (HFs). Dermal papilla (DP) plays a crucial role in HF development, growth, and regeneration. Activating DP can revive resting HFs. Augmenting WNT/β-catenin signaling stimulates HF growth. However, the factors responsible for activating resting HFs effectively are unclear. In thi

Forming giant planets around late-M dwarfs : Pebble accretion and planet-planet collision

We propose a pebble-driven core accretion scenario to explain the formation of giant planets around the late-M dwarfs of M∗=0.1-0.2 M⊙. In order to explore the optimal disk conditions for giant planet, we performed N-body simulations to investigate the growth and dynamical evolution of both single and multiple protoplanets in the disks with both inner viscously heated and outer stellar irradiated

The Concordance Index decomposition : A measure for a deeper understanding of survival prediction models

The Concordance Index (C-index) is a commonly used metric in Survival Analysis for evaluating the performance of a prediction model. In this paper, we propose a decomposition of the C-index into a weighted harmonic mean of two quantities: one for ranking observed events versus other observed events, and the other for ranking observed events versus censored cases. This decomposition enables a finer

DNA methylation risk score for type 2 diabetes is associated with gestational diabetes

BACKGROUND: Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to test whether a DNA methylation risk score (MRS) for T2DM was associated with GDM across ancestry and GDM criteria.METHODS: In two independent pregnancy cohorts, EPIPREG (n = 480) and EPIDG (n =

Human Genetic Variation at rs10071329 Correlates with Adiposity-related Traits, Modulates PPARGC1B Expression, and Alters Brown Adipocyte Function

Human genetic variation in PPARGC1B has been associated with adiposity, but the genetic variants that affect PPARGC1B expression have not been experimentally determined. Here, guided by previous observational data, we used CRISPR/Cas9 to scarlessly edit the alleles of the candidate causal genetic variant rs10071329 in a human brown adipocyte cell line (hBAs). Switching the rs10071329 genotype from