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Training after myocardial infarction : Lack of long-term effects on physical capacity and psychological variables

This study evaluated long-term effects of 12 weeks of supervised training, of at least 45 minutes duration with two sessions per week, on physical performance and psychological well-being after myocardial infarction (MI). Sixty-nine patients were randomized to either an exercise or a nonexercise group. Maximum exercise capacity 6 weeks post-MI was inversely related to the acute peak aspartate amin

Updated determination of αs(mτ 2) from τ decays

Using the most recent release of the ALEPH τ decay data, we present a very detailed phenomenological update of the αs(mτ 2) determination. We have exploited the sensitivity to the strong coupling in many different ways, exploring several complementary methodologies. All determinations turn out to be in excellent agreement, allowing us to extract a very reliable value of the strong coupling. We fin

Helicity antenna showers for hadron colliders

We present a complete set of helicity-dependent 2 → 3 antenna functions for QCD initial- and final-state radiation. The functions are implemented in the Vincia shower Monte Carlo framework and are used to generate showers for hadron-collider processes in which helicities are explicitly sampled (and conserved) at each step of the evolution. Although not capturing the full effects of spin correlatio

The correlation lengths and the order of the phase transition in three-dimensional Z 3 symmetric models

We present a high statistics Monte Carlo investigation of three-dimensional Z 3 symmetric models, which are related to SU(3) pure gauge theory at finite temperature. From the finite size scaling behaviour of bulk properties and the existence of metastable states, we conclude that these models exhibit a first-order phase transition. We have also performed detailed correlation length measurements i

Key-hiding on the ARM platform

To combat the problem of encryption key recovery from main memory using cold boot-attacks, various solutions has been suggested, but most of these have been implemented on the x86 architecture, which is not prevalent in the smartphone market, where instead ARM dominates. One existing solution does exist for the ARM architecture but it is limited to key sizes of 128 bits due to not being able to ut

Appropriating or hijacking creativity? Educational reform and creative learning in China

‘Creativity’ has become a buzzword throughout educational debates and strategy papers worldwide. By linking creativity to innovative capacity, it is commonly associated with the challenges and opportunities as generated by the knowledge economy. While the importance of creative approaches to learning is generally accepted, it has proven much more difficult to define and potentially assess skills a

Prostate cancer risk-associated single-nucleotide polymorphism affects prostate-specific antigen glycosylation and its function

BACKGROUND: Genetic association studies have reported single-nucleotide polymorphisms (SNPs) at chromosome 19q13.3 to be associated with prostate cancer (PCa) risk. Recently, the rs61752561 SNP (Asp84Asn substitution) in exon 3 of the kallikrein-related peptidase 3 (KLK3) gene encoding prostate-specific antigen (PSA) was reported to be strongly associated with PCa risk (P 2.3 108). However, the bi

Determinants of depressive mood in coronary artery disease patients with obstructive sleep apnea and response to continuous positive airway pressure treatment in non-sleepy and sleepy phenotypes in the RICCADSA cohort

We explored determinants of depressive mood in adults with coronary artery disease and obstructive sleep apnea and response to positive airway pressure treatment in sleepy and non-sleepy phenotypes. In this secondary analysis of the RICCADSA trial conducted in Sweden, 493 cardiac patients with obstructive sleep apnea (n = 386) or no obstructive sleep apnea (n = 107) with complete Epworth Sleepines

Comparing biologicals and small molecule drug therapies for chronic respiratory diseases : An EAACI Taskforce on Immunopharmacology position paper

Chronic airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), together with their comorbidities, bear a significant burden on public health. Increased appreciation of molecular networks underlying inflammatory airway disease needs to be translated into new therapies for distinct phenotypes not controlled by current treatment regimens. On the other hand, development of ne

Geographic origin and migration phenology of European red admirals (Vanessa atalanta) as revealed by stable isotopes

Background: Long-distance migration has evolved multiple times in different animal taxa. For insect migrants, the complete annual migration cycle covering several thousand kilometres, may be performed by several generations, each migrating part of the distance and reproducing. Different life-cycle stages and preferred orientation may thus, be found along the migration route. For migrating red admi

Aquaporin-4-dependent glymphatic solute transport in the rodent brain

The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-β. Influx of cerebrospinal fluid (CSF) depends upon the expression and perivascular localization of the astroglial water channel aquaporin-4 (AQP4). Prompted by a recent failure to find an effect of Aqp4 knock-out (KO) on CSF and interstitial fluid (ISF) tracer transport, five groups

Direct Lineage Reprogramming of Adult Mouse Fibroblast to Erythroid Progenitors

Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of cell fate determining and maturing factors. We previously set out to define the minimal set of factors necessary for instructing red blood cell development using direct lineage reprogramming of fibroblasts into induced erythroid progenitors/precursors