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Validation of an omega-3 substrate challenge absorption test as an indicator of global fat lipolysis

Introduction The coefficient of fat absorption (CFA) quantifies fat that remains in stool after digestion and is not a direct measure of lipolysis. CFA has been used to assess treatment of pancreatic insufficiency but does not correlate with pancreatic enzyme replacement therapy dose. We explored use of an omega-3 substrate absorption challenge test as a sensitive test of lipolysis and absorption.

Ten-year trends of immediate sequential bilateral cataract surgery (ISBCS) as reflected in the Swedish National Cataract Register

Purpose: To analyse trends of ISBCS reported to the Swedish National Cataract Register (NCR) over a 10-year period. Methods: Since 2010 the NCR contains social security number of all individuals in the list of parameters reported to NCR after each cataract procedure. Bilateral surgeries were mapped out using social security numbers. When dates of both-eye surgeries are identical for an individual

Arbuscular mycorrhizal fungi trigger danger-associated peptide signaling and inhibit carbon‒phosphorus exchange with nonhost plants

In soil, arbuscular mycorrhizal fungi (AMF) meet the roots of both host and presumed nonhost plants, but the interactional mechanisms of AMF with and functional relevance for nonhost plants is little known. Here we show AMF can colonize an individually grown nonhost plant, Arabidopsis thaliana, and suppress the growth of Arabidopsis and two nonhost Brassica crops. This inhibitory effect increased

Introduction

This edited volume discusses the emergence and development, and in some cases also the disappearance, of social movements and activism in the Swedish 1980s. The introductory chapter gives the background and aim of the volume and discusses why the Swedish case is interesting from a European perspective. The 1980s have often been described as a decade when the radical social movements of the 1960s a

Pluriversal spaces for decolonizing design : Exploring decolonial directions for participatory design

Decolonization is a situated effort as it relates to the relations of privilege, power, politics, and access (3P-A, in Albarrán González’s terms) between the people involved in design in relation to wider societies. This complexity creates certain challenges for how we can understand, learn about, and nurture decolonization in design towards pluriversality, since such decolonizing effort is based

Ingvar Carlson var en nyliberal pionjär

Socialdemokraternas tidigare ledare Ingvar Carlsson underskattar sin nyliberala pionjärinsats. ”Har han inte förstått vad han sysslat med som statsråd och statsminister?”, frågar sig professor Lars Jonung.

Fluorescence-Based Measurements of Two-Dimensional Affinity in Membrane Interfaces

Binding between ligands and receptors across cell contacts influences a range of biological processes including the formation of the immune synapse. The dissociation constant (Kd = 1/affinity) of the interaction corresponds to the concentration of ligands where half of the receptors in the contact have bound a ligand. In this chapter, we outline how to measure this two-dimensional affinity using m

Side effects of low-dose tamoxifen : results from a six-armed randomised controlled trial in healthy women

Background: Adherence to adjuvant tamoxifen therapy is suboptimal, and acceptance of tamoxifen for primary prevention is poor. Published results indicate effect of low-dose tamoxifen therapy. Using questionnaire data from a randomised controlled trial, we describe side effects of standard and low-dose tamoxifen in healthy women. Methods: In the KARISMA trial, 1440 healthy women were randomised to

Refugee Entrepreneurship : Towards a Nuanced Understanding of the Phenomenon

Forced cross-border migration and entrepreneurship have persisted as perennial themes throughout the annals of human history. However, the recent ‘refugee crisis’ has sparked a resurgence of interest in their interplay under the rubric of ‘refugee entrepreneurship’. While its territory is not entirely uncharted, a surge in scholarly urgency and heightened scientific production have significantly e

Separating Si phases from diagenetically-modified sediments through sequential leaching.

Silicon (Si) phases such as biogenic silica, lithogenic silicate and authigenic silica/silicate in marine sediments provide valuable information about past Si cycling. Wet-chemical sequential leaching methods are often applied to extract different Si phases from marine sediments to study Si diagenetic processes in shallow subsurface. The potential of this method to separate Si phases from deeply-b

Improving educational and reproductive outcomes for adolescent mothers in South Africa : A cross-sectional analysis towards realising policy goals

Adolescent mothers face numerous challenges. This study aimed to address the operationalisation of the new South African national policy for young mothers by testing the associations of potential protective provisions with three policy goals: School return, grade promotion, and pregnancy/HIV prevention. Adolescent mothers aged 12–24 from rural and urban communities of South Africa’s Eastern Cape c

False-positive recalls in the prospective Malmö Breast Tomosynthesis Screening Trial

Objectives: To evaluate the total number of false-positive recalls, including radiographic appearances and false-positive biopsies, in the Malmö Breast Tomosynthesis Screening Trial (MBTST). Methods: The prospective, population-based MBTST, with 14,848 participating women, was designed to compare one-view digital breast tomosynthesis (DBT) to two-view digital mammography (DM) in breast cancer scre

Peace Actions and Mainstream Media : Framing Nuclear Disarmament Protests in Welfare Sweden

This chapter investigates how reports in Swedish mainstream media framed the 1980s peace movement collective actions in Sweden. By revisiting press coverage of protest events, the analysis identifies the central characteristics of the framing. Primarily, the protests are found to be framed in positive terms and successfully conveyed what Charles Tilly and others have noted as key for a social move

“The Winter Palace” in Malmö : Subversive Activists, Welfare-State Anarchists, or Just a Slightly Radical Cultural Association?

The Winter Palace (TWP) was a venue and association within the left-wing alternative environment in Malmö between 1987–1989, with premises in the port area. The venue ran a pub and café; arranged concerts, public lectures, and movie screenings; broadcasted radio; published fanzines; and more. The idea was that the proceeds would be used to build a Southern Swedish center for anarchist propaganda a

The prognostic impact of IKZF1 deletions and UKALL genetic classifiers in paediatric B-cell precursor acute lymphoblastic leukaemia treated according to NOPHO 2008 protocols

We investigated 390 paediatric B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) patients treated according to NOPHO ALL 2008, regarding copy number alterations (CNA) of eight loci associated with adverse prognosis, including IKZF1. The impact on outcome was investigated for each locus individually, combined as CNA profiles and together with cytogenetic information. The presence of IKZF1 de

Investigating the effects of autonomy-supportive parenting practices on Italian young adolescent students’ motivation to defend victims of bullying : findings on the mediating roles of reactance, depression, anxiety, and stress

This study investigated the effect of autonomy-supportive parenting practices on young adolescents’ self-reported motivation to defend victims of bullying, and the possible mediating effects of factors such as reactance, anxiety, depression, and stress. Methods: Data were collected from 578 Italian public school students ages 10–14 (Mage = 11.8 years, 52% boys), who completed a survey in their cla

Cardiovascular effects of oxytocin and carbetocin at cesarean section. A prospective double-blind randomized study using noninvasive pulse wave analysis

Background: Oxytocin is routinely administered after delivery for prophylaxis and treatment of postpartum hemorrhage, but it is associated with considerable cardiovascular side-effects. Carbetocin, a synthetic oxytocin analogue, has a myometrial contraction effect of 60 min when given IV, compared with 16 min for oxytocin. Objective: To investigate whether there are differences in cardiovascular e